Gemcitabine Impurity 15

Name: Gemcitabine Impurity 15
Brand: Vaqora Chemicals
SKU: VQ-005029

About Gemcitabine Impurity 15

Gemcitabine Impurity 15 is an impurity of Gemcitabine carrying the CAS registry number 122111-01-7. Its molecular formula is C19H14F2O6 and its molecular weight is 376.3 g/mol. The IUPAC name is [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-oxooxolan-2-yl]methyl benzoate. Common synonyms include Gemcitabine Impurity 8.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Gemcitabine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Gemcitabine Impurity 15
Catalogue No.	VQ-005029
CAS Number	122111-01-7
IUPAC name	[(2R,3R)-3-benzoyloxy-4,4-difluoro-5-oxooxolan-2-yl]methyl benzoate
Molecular formula	C₁₉H₁₄F₂O₆
Molecular weight	376.3 g/mol
Exact mass	376.0758
Grade	Reference Standard
HSN code	38229090
InChIKey	SHHNEUNVMZNOID-HUUCEWRRSA-N
SMILES	C1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H](C(C(=O)O2)(F)F)OC(=O)C3=CC=CC=C3
PubChem CID	9821015

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 8
TPSA	78.9 Å²
Synonyms	2-deoxy-2,2-difluoro-d-erythro-pentafuranous-1-ulose-3,5-dibenzoate, 2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate, ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate, [(2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-oxotetrahydro-2-furanyl]methyl benzoate, (2R,3R)-2-[(benzoyloxy)methyl]-4,4-difluoro-5-oxooxolan-3-yl benzoate, (2R,3R)-2-((benzoyloxy)methyl)-4,4-difluoro-5-oxooxolan-3-yl benzoate, 2-Deoxy-2,2-difluoro-D-erythro-pentonic acid, A-lactone 3,5-dibenzoate, D-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-, g-lactone,3,5-dibenzoate, Gemcitabine Impurity 8, 2-Deoxyl-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate, 3,5-Bis(benzoyl)-2-deoxy-2,2-difluoro-1-oxoribose

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 122111-01-7

2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate, 95%

CAS: 122111-01-7
Formula: C₁₉H₁₄F₂O₆
MW: 376.3 g/mol

VQ-010564

Frequently asked questions

What is the CAS number of Gemcitabine Impurity 15?

The CAS Registry Number of Gemcitabine Impurity 15 is 122111-01-7. It is also known as 2-deoxy-2,2-difluoro-d-erythro-pentafuranous-1-ulose-3,5-dibenzoate, 2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate, ((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate.

What is the molecular formula and molecular weight of Gemcitabine Impurity 15?

Gemcitabine Impurity 15 has the molecular formula C19H14F2O6 and a molecular weight of 376.3 g/mol. Its IUPAC name is [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-oxooxolan-2-yl]methyl benzoate.

What is Gemcitabine Impurity 15 used for?

Gemcitabine Impurity 15 is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gemcitabine Impurity 15 can I order?

We supply Gemcitabine Impurity 15 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gemcitabine Impurity 15?

Yes. Every lot of Gemcitabine Impurity 15 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gemcitabine Impurity 15 be shipped internationally?

Yes. Gemcitabine Impurity 15 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.