Hydrocortisone (9b,11b)-Epoxide

Name: Hydrocortisone (9b,11b)-Epoxide
Brand: Vaqora Chemicals
SKU: VQ-022804

About Hydrocortisone (9b,11b)-Epoxide

Listed under CAS 10072-97-6, Hydrocortisone (9b,11b)-Epoxide is an impurity of Hydrocortisone available from Vaqora Chemicals. With the molecular formula C21H28O5, it has a molar mass of 360.4 g/mol. Alternative names: Hydrocortisone (9beta,11beta)-Epoxide and 9(11)-Epoxide Hydrocortisone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Hydrocortisone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone (9b,11b)-Epoxide
Catalogue No.	VQ-022804
CAS Number	10072-97-6
IUPAC name	(1S,2S,10S,11S,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-5-one
Molecular formula	C₂₁H₂₈O₅
Molecular weight	360.4 g/mol
Exact mass	360.1937
Grade	Reference Standard
HSN code	38229090
InChIKey	FJCQSIDXADHVFH-FEUSSREZSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]24[C@@H](O4)C[C@]5([C@H]3CC[C@@]5(C(=O)CO)O)C
PubChem CID	112075

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²
Synonyms	Hydrocortisone (9beta,11beta)-Epoxide, 9(11)-Epoxide Hydrocortisone, Hydrocortisone (9β,11β)-Epoxide, 9(11)-Epoxide Hydrocortisone, Hydrocortisone-9β,11β-epoxide, Pregn-4-ene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9beta,11beta)-, 9beta,11beta-Epoxy-17,21-dihydroxypregn-4-ene-3,20-dione, 17,21-dihydroxy-9,11-epoxypregn-4-ene-3,20-dione, 17,21-Dihydroxy-9beta,11beta-9,11-epoxypregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-, (9beta,11beta)- (9CI)

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone (9b,11b)-Epoxide?

The CAS Registry Number of Hydrocortisone (9b,11b)-Epoxide is 10072-97-6. It is also known as Hydrocortisone (9beta,11beta)-Epoxide, 9(11)-Epoxide Hydrocortisone, Hydrocortisone (9β,11β)-Epoxide.

What is the molecular formula and molecular weight of Hydrocortisone (9b,11b)-Epoxide?

Hydrocortisone (9b,11b)-Epoxide has the molecular formula C21H28O5 and a molecular weight of 360.4 g/mol. Its IUPAC name is (1S,2S,10S,11S,14R,15S,17S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-en-5-one.

What is Hydrocortisone (9b,11b)-Epoxide used for?

Hydrocortisone (9b,11b)-Epoxide is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone (9b,11b)-Epoxide can I order?

We supply Hydrocortisone (9b,11b)-Epoxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone (9b,11b)-Epoxide?

Yes. Every lot of Hydrocortisone (9b,11b)-Epoxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone (9b,11b)-Epoxide be shipped internationally?

Yes. Hydrocortisone (9b,11b)-Epoxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.