Hydrocortisone EP Impurity K

Name: Hydrocortisone EP Impurity K
Brand: Vaqora Chemicals
SKU: VQ-021234

About Hydrocortisone EP Impurity K

Listed under CAS 640-87-9, Hydrocortisone EP Impurity K is a pharmacopeial impurity of Hydrocortisone available from Vaqora Chemicals. Its molecular formula is C23H32O5 and its molecular weight is 388.5 g/mol. It is also known as 17a-Hydroxy-11-deoxycorticosterone-21-acetate or 17α-Hydroxy-11-deoxycorticosterone-21-acetate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Hydrocortisone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone EP Impurity K
Catalogue No.	VQ-021234
CAS Number	640-87-9
IUPAC name	[2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₃₂O₅
Molecular weight	388.5 g/mol
Exact mass	388.225
Grade	Reference Standard
HSN code	38229090
InChIKey	HPAKILCZTKWIFK-JZTHCNPZSA-N
SMILES	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID	101816

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 5
TPSA	80.7 Å²
Synonyms	17a-Hydroxy-11-deoxycorticosterone-21-acetate, 17α-Hydroxy-11-deoxycorticosterone-21-acetate, Cortexolone Impurity C, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione, 11-Deoxycortisol 21-acetate, cortexolone 21-acetate, Pregn-4-ene-3,20-dione, 21-(acetyloxy)-17-hydroxy-, 17-alpha,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate, 17-Hydroxy-3,20-dioxopregn-4-en-21-yl acetate, 17-Hydroxy-3,20-dioxopregn-4-en-21-yl Acetate (Reichstein's Substance S 21-Acetate), 11-Deoxy-17-hydrocorticosterone 21-acetate, Reichstein's S acetate

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone EP Impurity K?

The CAS Registry Number of Hydrocortisone EP Impurity K is 640-87-9. It is also known as 17a-Hydroxy-11-deoxycorticosterone-21-acetate, 17α-Hydroxy-11-deoxycorticosterone-21-acetate, Cortexolone Impurity C.

What is the molecular formula and molecular weight of Hydrocortisone EP Impurity K?

Hydrocortisone EP Impurity K has the molecular formula C23H32O5 and a molecular weight of 388.5 g/mol. Its IUPAC name is [2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is Hydrocortisone EP Impurity K used for?

Hydrocortisone EP Impurity K is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone EP Impurity K can I order?

We supply Hydrocortisone EP Impurity K in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone EP Impurity K?

Yes. Every lot of Hydrocortisone EP Impurity K is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone EP Impurity K be shipped internationally?

Yes. Hydrocortisone EP Impurity K is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.