Hydroxy Bupropion-d6

Name: Hydroxy Bupropion-d6
Brand: Vaqora Chemicals
SKU: VQ-029555

About Hydroxy Bupropion-d6

Vaqora Chemicals supplies Hydroxy Bupropion-d6, a stable isotope labelled analogue related to Bupropion registered under CAS number 1216893-18-3. The compound has the formula C13H18ClNO2, corresponding to a molecular weight of 261.78 g/mol. Its systematic (IUPAC) name is 2-(3-chlorophenyl)-3-methyl-5,5-bis(trideuteriomethyl)morpholin-2-ol. Alternative names: Bupropion morpholinol D6 and Bupropion morpholinol-d6.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Bupropion and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Bupropion-d6
Catalogue No.	VQ-029555
CAS Number	1216893-18-3
IUPAC name	2-(3-chlorophenyl)-3-methyl-5,5-bis(trideuteriomethyl)morpholin-2-ol
Molecular formula	C₁₃H₁₈ClNO₂
Molecular weight	261.78 g/mol
Exact mass	261.1403
Grade	Reference Standard
HSN code	38229090
InChIKey	RCOBKSKAZMVBHT-XERRXZQWSA-N
SMILES	[2H]C([2H])([2H])C1(COC(C(N1)C)(C2=CC(=CC=C2)Cl)O)C([2H])([2H])[2H]
PubChem CID	45358931

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Bupropion-d6?

The CAS Registry Number of Hydroxy Bupropion-d6 is 1216893-18-3. It is also known as Bupropion morpholinol D6, Bupropion morpholinol-d6, 2-(3-chlorophenyl)-3-methyl-5,5-bis(methyl-d3)morpholin-2-ol.

What is the molecular formula and molecular weight of Hydroxy Bupropion-d6?

Hydroxy Bupropion-d6 has the molecular formula C13H18ClNO2 and a molecular weight of 261.78 g/mol. Its IUPAC name is 2-(3-chlorophenyl)-3-methyl-5,5-bis(trideuteriomethyl)morpholin-2-ol.

What is Hydroxy Bupropion-d6 used for?

Hydroxy Bupropion-d6 is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Bupropion-d6 can I order?

We supply Hydroxy Bupropion-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Bupropion-d6?

Yes. Every lot of Hydroxy Bupropion-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Bupropion-d6 be shipped internationally?

Yes. Hydroxy Bupropion-d6 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.