Ibrutinib N-Despiperidinyl Impurity

Name: Ibrutinib N-Despiperidinyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-007178

About Ibrutinib N-Despiperidinyl Impurity

Ibrutinib N-Despiperidinyl Impurity is a metabolite or degradation product of Ibrutinib carrying the CAS registry number 330786-24-8. Its molecular formula is C17H13N5O and its molecular weight is 303.32 g/mol. Its systematic (IUPAC) name is 3-(4-phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine. Alternative names: Ibrutinib deacryloylpiperidine and Ibrutinib Impurity 8.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ibrutinib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ibrutinib N-Despiperidinyl Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ibrutinib N-Despiperidinyl Impurity
Catalogue No.	VQ-007178
CAS Number	330786-24-8
IUPAC name	3-(4-phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine
Molecular formula	C₁₇H₁₃N₅O
Molecular weight	303.32 g/mol
Exact mass	303.112
Grade	Reference Standard
HSN code	38229090
InChIKey	YYVUOZULIDAKRN-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=C4C(=NC=NC4=NN3)N
PubChem CID	22346757

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 5
TPSA	89.7 Å²
Synonyms	3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Ibrutinib deacryloylpiperidine, Ibrutinib Impurity 8, 3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine, Ibrutinib N-2, 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine, Ibrutinib Impurity 13, IBT4A, 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-, 3-(4-phenoxy-phenyl)-1(2)H-pyrazole, 3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4 d)pyrimidin-4-amine, 1H-Pyrazolo(3,4-d)pyrimidin-4-amine, 3-(4-phenoxyphenyl)-

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibrutinib N-Despiperidinyl Impurity?

The CAS Registry Number of Ibrutinib N-Despiperidinyl Impurity is 330786-24-8. It is also known as 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Ibrutinib deacryloylpiperidine, Ibrutinib Impurity 8.

What is the molecular formula and molecular weight of Ibrutinib N-Despiperidinyl Impurity?

Ibrutinib N-Despiperidinyl Impurity has the molecular formula C17H13N5O and a molecular weight of 303.32 g/mol. Its IUPAC name is 3-(4-phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine.

What is Ibrutinib N-Despiperidinyl Impurity used for?

Ibrutinib N-Despiperidinyl Impurity is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibrutinib N-Despiperidinyl Impurity can I order?

We supply Ibrutinib N-Despiperidinyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibrutinib N-Despiperidinyl Impurity?

Yes. Every lot of Ibrutinib N-Despiperidinyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibrutinib N-Despiperidinyl Impurity be shipped internationally?

Yes. Ibrutinib N-Despiperidinyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.