Imatinib EP Impurity B

Name: Imatinib EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-026144

About Imatinib EP Impurity B

Imatinib EP Impurity B is a pharmacopeial impurity of Imatinib carrying the CAS registry number 581076-65-5. Formula C21H28N6O, molecular weight 380.5 g/mol. Systematically, it is named N-[3-(diaminomethylideneamino)-4-methylphenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide. It is also known as Imatinib Guanidino Impurity or Imatinib Mesylate - Impurity B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Imatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Imatinib EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Imatinib EP Impurity B
Catalogue No.	VQ-026144
CAS Number	581076-65-5
IUPAC name	N-[3-(diaminomethylideneamino)-4-methylphenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide
Molecular formula	C₂₁H₂₈N₆O
Molecular weight	380.5 g/mol
Exact mass	380.2325
Grade	Reference Standard
HSN code	38229090
InChIKey	AJNIAMJOBVYWFM-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)N=C(N)N
PubChem CID	29980915

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 4
TPSA	100 Å²
Synonyms	Imatinib Guanidino Impurity, Imatinib Mesylate - Impurity B, Imatinib Mesylate Impurity B, N-[3-[(Aminoiminomethyl)amino]-4-methylphenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide, N-(3-((Aminoiminomethyl)amino)-4-methylphenyl)-4-((4-methyl-1-piperazinyl)methyl)benzamide, N-[2-Methyl-5-[[4-[(4-methylpiperazin-1-yl)methyl]benzoyl]amino]phenyl]guanidine, N-(3-guanidino-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide, N-(3-guanidino-4-methyl-phenyl)-4-(4-methyl-piperazin-1-ylmethyl)-benz-amide, N-(3-guanidino-4-methyl-phenyl)-4-(4-methyl-piperazin-1-ylmethyl)-benzamide, N-(3-guanidino-4-methyl-phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Imatinib EP Impurity B?

The CAS Registry Number of Imatinib EP Impurity B is 581076-65-5. It is also known as Imatinib Guanidino Impurity, Imatinib Mesylate - Impurity B, Imatinib Mesylate Impurity B.

What is the molecular formula and molecular weight of Imatinib EP Impurity B?

Imatinib EP Impurity B has the molecular formula C21H28N6O and a molecular weight of 380.5 g/mol. Its IUPAC name is N-[3-(diaminomethylideneamino)-4-methylphenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide.

What is Imatinib EP Impurity B used for?

Imatinib EP Impurity B is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Imatinib EP Impurity B can I order?

We supply Imatinib EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Imatinib EP Impurity B?

Yes. Every lot of Imatinib EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Imatinib EP Impurity B be shipped internationally?

Yes. We export Imatinib EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.