Iodixanol EP Impurity A (Free Base)

Name: Iodixanol EP Impurity A (Free Base)
Brand: Vaqora Chemicals
SKU: VQ-026172

About Iodixanol EP Impurity A (Free Base)

Iodixanol EP Impurity A (Free Base) (CAS 66108-95-0) is a pharmacopeial impurity of Iohexol offered by Vaqora Chemicals. With the molecular formula C19H26I3N3O9, it has a molar mass of 821.1 g/mol. The IUPAC name is 5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide. Common synonyms include Iohexol and Iodixanol EP Impurity A.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Iohexol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Iohexol

View every impurity, metabolite and intermediate we list for Iohexol.

Iohexol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Iodixanol EP Impurity A (Free Base)
Catalogue No.	VQ-026172
CAS Number	66108-95-0
IUPAC name	5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
Molecular formula	C₁₉H₂₆I₃N₃O₉
Molecular weight	821.1 g/mol
Exact mass	820.8803
Grade	Reference Standard
HSN code	38229090
InChIKey	NTHXOOBQLCIOLC-UHFFFAOYSA-N
SMILES	CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
PubChem CID	3730

Physical properties
Physical form	Solid
LogP (XLogP3)	-3
H-bond donors / acceptors	8 / 9
TPSA	200 Å²
Synonyms	Iohexol, Iodixanol EP Impurity A, Omnipaque 240, Omnipaque 140, Omnipaque 180, Omnipaque 300, Omnipaque 350, Omnipaque 70, Omnipaque 210, Iohexol 350, Histodenz(TM), nonionic density gradient medium

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Iodixanol EP Impurity A (Free Base)?

The CAS Registry Number of Iodixanol EP Impurity A (Free Base) is 66108-95-0. It is also known as Iohexol, Iodixanol EP Impurity A, Omnipaque 240.

What is the molecular formula and molecular weight of Iodixanol EP Impurity A (Free Base)?

Iodixanol EP Impurity A (Free Base) has the molecular formula C19H26I3N3O9 and a molecular weight of 821.1 g/mol. Its IUPAC name is 5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide.

What is Iodixanol EP Impurity A (Free Base) used for?

Iodixanol EP Impurity A (Free Base) is supplied as a characterised reference material related to Iohexol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Iodixanol EP Impurity A (Free Base) can I order?

We supply Iodixanol EP Impurity A (Free Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Iodixanol EP Impurity A (Free Base)?

Yes. Every lot of Iodixanol EP Impurity A (Free Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Iodixanol EP Impurity A (Free Base) be shipped internationally?

Yes. Iodixanol EP Impurity A (Free Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.