Irinotecan EP Impurity B

Name: Irinotecan EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021052

About Irinotecan EP Impurity B

Irinotecan EP Impurity B is a pharmacopeial impurity of Camptothecin carrying the CAS registry number 19685-09-7. Formula C20H16N2O5, molecular weight 364.4 g/mol. It is also known as 10-Hydroxycamptothecin or 10-Hydroxy Camptothecin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Camptothecin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Irinotecan EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Camptothecin

View every impurity, metabolite and intermediate we list for Camptothecin.

Camptothecin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Irinotecan EP Impurity B
Catalogue No.	VQ-021052
CAS Number	19685-09-7
IUPAC name	(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Molecular formula	C₂₀H₁₆N₂O₅
Molecular weight	364.4 g/mol
Exact mass	364.1059
Grade	Reference Standard
HSN code	38229090
InChIKey	HAWSQZCWOQZXHI-FQEVSTJZSA-N
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
PubChem CID	97226

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	2 / 6
TPSA	100 Å²
Synonyms	10-Hydroxycamptothecin, 10-Hydroxy Camptothecin, Camptothecin 10-hydroxy Impurity, Irinotecan - Impurity B, (S)-10-Hydroxycamptothecin, Hydroxycamptothecin, 10-hydroxycamptothecine, 10-HCPT, Hydroxycamptothecine, Camptothecin, hydroxy-, Camptothecine, 10-hydroxy-, 10-Hydroxy-Camptothecin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Irinotecan EP Impurity B?

The CAS Registry Number of Irinotecan EP Impurity B is 19685-09-7. It is also known as 10-Hydroxycamptothecin, 10-Hydroxy Camptothecin, Camptothecin 10-hydroxy Impurity.

What is the molecular formula and molecular weight of Irinotecan EP Impurity B?

Irinotecan EP Impurity B has the molecular formula C20H16N2O5 and a molecular weight of 364.4 g/mol. Its IUPAC name is (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione.

What is Irinotecan EP Impurity B used for?

Irinotecan EP Impurity B is supplied as a characterised reference material related to Camptothecin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Irinotecan EP Impurity B can I order?

We supply Irinotecan EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Irinotecan EP Impurity B?

Yes. Every lot of Irinotecan EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Irinotecan EP Impurity B be shipped internationally?

Yes. Irinotecan EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.