Irinotecan EP Impurity F

Name: Irinotecan EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-021242

About Irinotecan EP Impurity F

Listed under CAS 78287-27-1, Irinotecan EP Impurity F is a pharmacopeial impurity of Irinotecan available from Vaqora Chemicals. Formula C22H20N2O4, molecular weight 376.4 g/mol. Common synonyms include 7-ethyl Camptothecin and Camptothecin 7-Ethyl Impurity.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Irinotecan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Irinotecan EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Irinotecan

View every impurity, metabolite and intermediate we list for Irinotecan.

Irinotecan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Irinotecan EP Impurity F
Catalogue No.	VQ-021242
CAS Number	78287-27-1
IUPAC name	(19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Molecular formula	C₂₂H₂₀N₂O₄
Molecular weight	376.4 g/mol
Exact mass	376.1423
Grade	Reference Standard
HSN code	38229090
InChIKey	MYQKIWCVEPUPIL-QFIPXVFZSA-N
SMILES	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC=CC=C51
PubChem CID	127584

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 5
TPSA	79.7 Å²
Synonyms	7-ethyl Camptothecin, Camptothecin 7-Ethyl Impurity, 7-Ethylcamptothecin, SN-22, SN 22, 7-Ethyl-20(S)-camptothecin, 7-ethyl-camptothecin, 7-Ethyl-20(S)-camp, 7-Ethylcamptothecin, AldrichCPR, 4,11-Diethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled

Precautionary statements: P261, P262, P264, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P316, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Irinotecan EP Impurity F?

The CAS Registry Number of Irinotecan EP Impurity F is 78287-27-1. It is also known as 7-ethyl Camptothecin, Camptothecin 7-Ethyl Impurity, 7-Ethylcamptothecin.

What is the molecular formula and molecular weight of Irinotecan EP Impurity F?

Irinotecan EP Impurity F has the molecular formula C22H20N2O4 and a molecular weight of 376.4 g/mol. Its IUPAC name is (19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.

What is Irinotecan EP Impurity F used for?

Irinotecan EP Impurity F is supplied as a characterised reference material related to Irinotecan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Irinotecan EP Impurity F can I order?

We supply Irinotecan EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Irinotecan EP Impurity F?

Yes. Every lot of Irinotecan EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Irinotecan EP Impurity F be shipped internationally?

Yes. Irinotecan EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.