Isavuconazole-d4

Name: Isavuconazole-d4
Brand: Vaqora Chemicals
SKU: VQ-031251

About Isavuconazole-d4

Isavuconazole-d4 is a stable isotope labelled analogue related to Isavuconazole carrying the CAS registry number 1346598-58-0. With the molecular formula C22H17F2N5OS, it has a molar mass of 441.5 g/mol. It is also known as Isavuconazole-d4 (RR) or Isavuconazole D4 (RR SS).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Isavuconazole and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Isavuconazole-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Isavuconazole

View every impurity, metabolite and intermediate we list for Isavuconazole.

Isavuconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Isavuconazole-d4
Catalogue No.	VQ-031251
CAS Number	1346598-58-0
IUPAC name	2,3,5,6-tetradeuterio-4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
Molecular formula	C₂₂H₁₇F₂N₅OS
Molecular weight	441.5 g/mol
Exact mass	441.1373
Grade	Reference Standard
HSN code	38229090
InChIKey	DDFOUSQFMYRUQK-KUXFOAEVSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C#N)[2H])[2H])C2=CSC(=N2)[C@H](C)[C@](CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O)[2H]
PubChem CID	71749534

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 8
TPSA	116 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isavuconazole-d4?

The CAS Registry Number of Isavuconazole-d4 is 1346598-58-0. It is also known as Isavuconazole-d4 (RR), Isavuconazole D4 (RR SS).

What is the molecular formula and molecular weight of Isavuconazole-d4?

Isavuconazole-d4 has the molecular formula C22H17F2N5OS and a molecular weight of 441.5 g/mol. Its IUPAC name is 2,3,5,6-tetradeuterio-4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile.

What is Isavuconazole-d4 used for?

Isavuconazole-d4 is supplied as a characterised reference material related to Isavuconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isavuconazole-d4 can I order?

We supply Isavuconazole-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isavuconazole-d4?

Yes. Every lot of Isavuconazole-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isavuconazole-d4 be shipped internationally?

Yes. Isavuconazole-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.