Isosilybin

Name: Isosilybin
Brand: Vaqora Chemicals
SKU: VQ-031277

About Isosilybin

Vaqora Chemicals supplies Isosilybin, a high-purity reference standard of Isosilybin registered under CAS number 72581-71-6. With the molecular formula C25H22O10, it has a molar mass of 482.4 g/mol. Common synonyms include Isosilybinin and EX-A8002P.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Isosilybin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Isosilybin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Isosilybin

View every impurity, metabolite and intermediate we list for Isosilybin.

Isosilybin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isosilybin
Catalogue No.	VQ-031277
CAS Number	72581-71-6
IUPAC name	(2R,3R)-3,5,7-trihydroxy-2-[2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula	C₂₅H₂₂O₁₀
Molecular weight	482.4 g/mol
Exact mass	482.1213
Grade	Reference Standard
HSN code	38229090
InChIKey	FDQAOULAVFHKBX-DBMPWETRSA-N
SMILES	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=CC(=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	21723007

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	5 / 10
TPSA	155 Å²
Synonyms	Isosilybinin, EX-A8002P, Isosilibinin, isosilybine, Isosilybin (Mixture of Diastereomers), (2R,3R)-3,5,7-trihydrox, Isosilybin (isomeric mixture of isosilybin A&B)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isosilybin?

The CAS Registry Number of Isosilybin is 72581-71-6. It is also known as Isosilybinin, EX-A8002P, Isosilibinin.

What is the molecular formula and molecular weight of Isosilybin?

Isosilybin has the molecular formula C25H22O10 and a molecular weight of 482.4 g/mol. Its IUPAC name is (2R,3R)-3,5,7-trihydroxy-2-[2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one.

What is Isosilybin used for?

Isosilybin is supplied as a characterised reference material related to Isosilybin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isosilybin can I order?

We supply Isosilybin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isosilybin?

Yes. Every lot of Isosilybin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isosilybin be shipped internationally?

Yes. Isosilybin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.