Isosorbide

Name: Isosorbide
Brand: Vaqora Chemicals
SKU: VQ-031279

About Isosorbide

Isosorbide (CAS 652-67-5) is a high-purity reference standard of Isosorbide offered by Vaqora Chemicals. Formula C6H10O4, molecular weight 146.14 g/mol. Systematically, it is named (3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol. Common synonyms include Isobide and 1,4:3,6-Dianhydro-D-glucitol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Isosorbide standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Isosorbide

View every impurity, metabolite and intermediate we list for Isosorbide.

Isosorbide impurities

Specifications & identifiers

Chemical identifiers
Product name	Isosorbide
Catalogue No.	VQ-031279
CAS Number	652-67-5
IUPAC name	(3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
Molecular formula	C₆H₁₀O₄
Molecular weight	146.14 g/mol
Exact mass	146.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	KLDXJTOLSGUMSJ-JGWLITMVSA-N
SMILES	C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O)O
PubChem CID	12597

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.4
H-bond donors / acceptors	2 / 4
TPSA	58.9 Å²
Synonyms	Isobide, 1,4:3,6-Dianhydro-D-glucitol, Hydronol, Ismotic, (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol, (+)-D-Isosorbide, D-Glucitol, 1,4:3,6-dianhydro-, 1,4:3,6-Dianhydro-D-sorbitol, 1,4:3,6-Dianhydrosorbitol, Glucitol, 1,4:3,6-dianhydro-, D-, (3R,3aR,6S,6aR)-hexahydrofuro(3,2-b)furan-3,6-diol, GlyTouCan:G82967ZA

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isosorbide?

The CAS Registry Number of Isosorbide is 652-67-5. It is also known as Isobide, 1,4:3,6-Dianhydro-D-glucitol, Hydronol.

What is the molecular formula and molecular weight of Isosorbide?

Isosorbide has the molecular formula C6H10O4 and a molecular weight of 146.14 g/mol. Its IUPAC name is (3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol.

What is Isosorbide used for?

Isosorbide is supplied as a characterised reference material related to Isosorbide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isosorbide can I order?

We supply Isosorbide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isosorbide?

Yes. Every lot of Isosorbide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isosorbide be shipped internationally?

Yes. We export Isosorbide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.