Isotretinoin Impurity A

Name: Isotretinoin Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005109

About Isotretinoin Impurity A

Isotretinoin Impurity A is an impurity of Isotretinoin carrying the CAS registry number 302-79-4. Its molecular formula is C20H28O2 and its molecular weight is 300.4 g/mol. The IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Common synonyms include all-(E)-Retinoic acid and trans-Retinoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Isotretinoin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Isotretinoin Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isotretinoin Impurity A
Catalogue No.	VQ-005109
CAS Number	302-79-4
Other CAS	13497-05-7, 22232-80-0, 454221-38-6
IUPAC name	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular formula	C₂₀H₂₈O₂
Molecular weight	300.4 g/mol
Exact mass	300.2089
Grade	Reference Standard
HSN code	38229090
InChIKey	SHGAZHPCJJPHSC-YCNIQYBTSA-N
SMILES	CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
PubChem CID	444795

Physical properties
Physical form	Solid
LogP (XLogP3)	6.3
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	all-(E)-Retinoic acid, trans-Retinoic acid, all-trans-Retinoic acid, all-trans-Tretinoin, all-trans-Vitamin A acid, all-trans-β-Retinoic acid, (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, Tretinoin, Vitamin A Acid, ATRA, Aberel, Avita

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 302-79-4

Retinoic acid, 93%

CAS: 302-79-4
Formula: C₂₀H₂₈O₂
MW: 300.4 g/mol

VQ-002960

Retinoic acid, 98%+

CAS: 302-79-4
Formula: C₂₀H₂₈O₂
MW: 300.4 g/mol

VQ-002961

Frequently asked questions

What is the CAS number of Isotretinoin Impurity A?

The CAS Registry Number of Isotretinoin Impurity A is 302-79-4. It is also known as all-(E)-Retinoic acid, trans-Retinoic acid, all-trans-Retinoic acid.

What is the molecular formula and molecular weight of Isotretinoin Impurity A?

Isotretinoin Impurity A has the molecular formula C20H28O2 and a molecular weight of 300.4 g/mol. Its IUPAC name is (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid.

What is Isotretinoin Impurity A used for?

Isotretinoin Impurity A is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isotretinoin Impurity A can I order?

We supply Isotretinoin Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isotretinoin Impurity A?

Yes. Every lot of Isotretinoin Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isotretinoin Impurity A be shipped internationally?

Yes. Isotretinoin Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.