Ivosidenib WS

Name: Ivosidenib WS
Brand: Vaqora Chemicals
SKU: VQ-007513

About Ivosidenib WS

Listed under CAS 1448347-49-6, Ivosidenib WS is a high-purity reference standard of Ivosidenib available from Vaqora Chemicals. The compound has the formula C28H22ClF3N6O3, corresponding to a molecular weight of 583.0 g/mol. It is also known as AG 120 or RG 120.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Ivosidenib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ivosidenib

View every impurity, metabolite and intermediate we list for Ivosidenib.

Ivosidenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ivosidenib WS
Catalogue No.	VQ-007513
CAS Number	1448347-49-6
IUPAC name	(2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide
Molecular formula	C₂₈H₂₂ClF₃N₆O₃
Molecular weight	583 g/mol
Exact mass	582.1394
Grade	Reference Standard
HSN code	38229090
InChIKey	WIJZXSAJMHAVGX-DHLKQENFSA-N
SMILES	C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
PubChem CID	71657455

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	1 / 9
TPSA	119 Å²
Synonyms	AG 120, RG 120, Ivosidenib, AG-120, US9850277, Compound 176, C28H22ClF3N6O3, Tibsovo (TN), Ivosidenib (USAN/INN), Glycinamide, 1-(4-cyano-, Ivosidenib (JAN/USAN/INN), EX-A992, IV3

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ivosidenib WS?

The CAS Registry Number of Ivosidenib WS is 1448347-49-6. It is also known as AG 120, RG 120, Ivosidenib.

What is the molecular formula and molecular weight of Ivosidenib WS?

Ivosidenib WS has the molecular formula C28H22ClF3N6O3 and a molecular weight of 583 g/mol. Its IUPAC name is (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide.

What is Ivosidenib WS used for?

Ivosidenib WS is supplied as a characterised reference material related to Ivosidenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ivosidenib WS can I order?

We supply Ivosidenib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ivosidenib WS?

Yes. Every lot of Ivosidenib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ivosidenib WS be shipped internationally?

Yes. Ivosidenib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.