Ketoconazole

Name: Ketoconazole
Brand: Vaqora Chemicals
SKU: VQ-007514

About Ketoconazole

Ketoconazole is a high-purity reference standard of Ketoconazole carrying the CAS registry number 65277-42-1. With the molecular formula C26H28Cl2N4O4, it has a molar mass of 531.4 g/mol. It is also known as Brizoral or Fungarest.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Ketoconazole, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ketoconazole is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole
Catalogue No.	VQ-007514
CAS Number	65277-42-1
IUPAC name	1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	531.4 g/mol
Exact mass	530.1488
Grade	Reference Standard
HSN code	38229090
InChIKey	XMAYWYJOQHXEEK-ZEQKJWHPSA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@@H]3CO[C@@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID	47576

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²
Synonyms	Brizoral, Fungarest, Fungoral, Ketoderm, Ketoisdin, Ketozoral, (±)-Ketoconazole, Micosin Nizaral, Nizoral, Nizral, Onofin K, Orifungal M

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 65277-42-1

IP/BP/USP

Ketoconazole

CAS: 65277-42-1
Formula: C₂₆H₂₈Cl₂N₄O₄
MW: 531.4 g/mol

VQ-003971

Ketoconazole, 98%

CAS: 65277-42-1
Formula: C₂₆H₂₈Cl₂N₄O₄
MW: 531.4 g/mol

VQ-012206

Frequently asked questions

What is the CAS number of Ketoconazole?

The CAS Registry Number of Ketoconazole is 65277-42-1. It is also known as Brizoral, Fungarest, Fungoral.

What is the molecular formula and molecular weight of Ketoconazole?

Ketoconazole has the molecular formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. Its IUPAC name is 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is Ketoconazole used for?

Ketoconazole is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole can I order?

We supply Ketoconazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole?

Yes. Every lot of Ketoconazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole be shipped internationally?

Yes. Ketoconazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.