Ketoconazole

Name: Ketoconazole
Brand: Vaqora Chemicals
SKU: VQ-003971

About Ketoconazole

Listed under CAS 65277-42-1, Ketoconazole is an anti-infective API available from Vaqora Chemicals (IP/BP/USP grade) at a purity of 98.0%. Formula C26H28Cl2N4O4, molecular weight 531.4 g/mol. Alternative names: Nizoral and Panfungol.

In its supplied form it is a white or almost white powder. Store in a tightly closed container in a cool, dry and well-ventilated place. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our antiviral, antifungal and antiparasitic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Typical end-use sectors are pharmaceutical manufacturing.

Vaqora Chemicals supplies Ketoconazole in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Anti-infective formulations
Generic drug development
Formulation R&D

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole
Catalogue No.	VQ-003971
CAS Number	65277-42-1
IUPAC name	1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	531.4 g/mol
Exact mass	530.1488
Grade	IP/BP/USP
Purity / assay	98.0%
HSN code	2933
InChIKey	XMAYWYJOQHXEEK-ZEQKJWHPSA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@@H]3CO[C@@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID	47576

Physical properties
Physical form	Powder
Appearance	White or almost white powder
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²
Synonyms	Nizoral, Panfungol, Fungoral, Ketoisdin, Orifungal M, Nizoral a-D, Ketoconazol, Dandrazol, Ketopine, Daktarin gold, Daktarin intensiv, Ketosidin

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 65277-42-1

Reference Standard

Ketoconazole

CAS: 65277-42-1
Formula: C₂₆H₂₈Cl₂N₄O₄
MW: 531.4 g/mol

In stock

Ketoconazole, 98%

CAS: 65277-42-1
Formula: C₂₆H₂₈Cl₂N₄O₄
MW: 531.4 g/mol

VQ-012206

Frequently asked questions

What is the CAS number of Ketoconazole?

The CAS Registry Number of Ketoconazole is 65277-42-1. It is also known as Nizoral, Panfungol, Fungoral.

What is the molecular formula and molecular weight of Ketoconazole?

Ketoconazole has the molecular formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. Its IUPAC name is 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is Ketoconazole used for?

Ketoconazole is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole can I order?

We supply Ketoconazole in IP/BP/USP (98.0%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole?

Yes. Every lot of Ketoconazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole be shipped internationally?

Yes. Ketoconazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.