Ketotifen EP Impurity B

Name: Ketotifen EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022902

About Ketotifen EP Impurity B

Ketotifen EP Impurity B (CAS 59743-88-3) is a pharmacopeial impurity of Ketotifen offered by Vaqora Chemicals. With the molecular formula C20H23NO2S, it has a molar mass of 341.5 g/mol. Systematically, it is named 8-methoxy-2-(1-methylpiperidin-4-yl)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ol. Alternative names: Ketotifen Fumarate EP Impurity B and Ketotifen Fumarate - Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Ketotifen impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ketotifen EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ketotifen

View every impurity, metabolite and intermediate we list for Ketotifen.

Ketotifen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketotifen EP Impurity B
Catalogue No.	VQ-022902
CAS Number	59743-88-3
IUPAC name	8-methoxy-2-(1-methylpiperidin-4-yl)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ol
Molecular formula	C₂₀H₂₃NO₂S
Molecular weight	341.5 g/mol
Exact mass	341.145
Grade	Reference Standard
HSN code	38229090
InChIKey	AAYKXJAFSKIHRK-UHFFFAOYSA-N
SMILES	CN1CCC(CC1)C2(C3=C(C(=CC4=CC=CC=C42)OC)SC=C3)O
PubChem CID	108389

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 4
TPSA	60.9 Å²
Synonyms	Ketotifen Fumarate EP Impurity B, Ketotifen Fumarate - Impurity B, 10-Methoxy-4-(1-methylpiperidin-4-yl)-4H-benzo(4.5)cyclohepta(1,2-b)thiophene-4-ol, 10-methoxy-4-(1-methylpiperidin-4-yl)-4H-benzo[4.5]cyclohepta[1,2-b]thiophene-4-ol, 10-methoxy-4-(1-methylpiperidin-4-yl)-4h-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol, 10-methoxy-4-(1-methylpiperidin-4-yl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol, 4-Hydroxy-10-methoxy-4-(1-methyl-4-piperidinyl)-4H-benzo(4,5)cyclohepta[1,2-b]thiophene, 10-methoxy-4-(1-methyl-4-piperidyl)-4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol, (4RS)-10-Methoxy-4-(1-methylpiperidin-4-yl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol, 10-methoxy-4-(1-methyl-4-piperidinyl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol, 10-Methoxy-4-(1-methyl-4-piperidinyl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol, 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol, 10-methoxy-4-(1-methyl-4-piperidinyl)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketotifen EP Impurity B?

The CAS Registry Number of Ketotifen EP Impurity B is 59743-88-3. It is also known as Ketotifen Fumarate EP Impurity B, Ketotifen Fumarate - Impurity B, 10-Methoxy-4-(1-methylpiperidin-4-yl)-4H-benzo(4.5)cyclohepta(1,2-b)thiophene-4-ol.

What is the molecular formula and molecular weight of Ketotifen EP Impurity B?

Ketotifen EP Impurity B has the molecular formula C20H23NO2S and a molecular weight of 341.5 g/mol. Its IUPAC name is 8-methoxy-2-(1-methylpiperidin-4-yl)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ol.

What is Ketotifen EP Impurity B used for?

Ketotifen EP Impurity B is supplied as a characterised reference material related to Ketotifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketotifen EP Impurity B can I order?

We supply Ketotifen EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketotifen EP Impurity B?

Yes. Every lot of Ketotifen EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketotifen EP Impurity B be shipped internationally?

Yes. Ketotifen EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.