L-Leucine-d10

Name: L-Leucine-d10
Brand: Vaqora Chemicals
SKU: VQ-041230

About L-Leucine-d10

L-Leucine-d10 (CAS 106972-44-5) is a stable isotope labelled analogue related to Leucine offered by Vaqora Chemicals. Its molecular formula is C6H13NO2 and its molecular weight is 141.23 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-2,3,3,4,5,5,5-heptadeuterio-4-(trideuteriomethyl)pentanoic acid. Common synonyms include Deuterated L-leucine and L-Leucine-2,3,3,4,5,5,5,6,6,6-d10.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Leucine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer L-Leucine-d10 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Leucine

View every impurity, metabolite and intermediate we list for Leucine.

Leucine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	L-Leucine-d10
Catalogue No.	VQ-041230
CAS Number	106972-44-5
IUPAC name	(2S)-2-amino-2,3,3,4,5,5,5-heptadeuterio-4-(trideuteriomethyl)pentanoic acid
Molecular formula	C₆H₁₃NO₂
Molecular weight	141.23 g/mol
Exact mass	141.1574
Grade	Reference Standard
HSN code	38229090
InChIKey	ROHFNLRQFUQHCH-ZWFPVXGPSA-N
SMILES	[2H][C@@](C(=O)O)(C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N
PubChem CID	16213587

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-Leucine-d10?

The CAS Registry Number of L-Leucine-d10 is 106972-44-5. It is also known as Deuterated L-leucine, L-Leucine-2,3,3,4,5,5,5,6,6,6-d10, TMIJ-0081.

What is the molecular formula and molecular weight of L-Leucine-d10?

L-Leucine-d10 has the molecular formula C6H13NO2 and a molecular weight of 141.23 g/mol. Its IUPAC name is (2S)-2-amino-2,3,3,4,5,5,5-heptadeuterio-4-(trideuteriomethyl)pentanoic acid.

What is L-Leucine-d10 used for?

L-Leucine-d10 is supplied as a characterised reference material related to Leucine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-Leucine-d10 can I order?

We supply L-Leucine-d10 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-Leucine-d10?

Yes. Every lot of L-Leucine-d10 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-Leucine-d10 be shipped internationally?

Yes. We export L-Leucine-d10 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.