Leuprolide impurity 4

Name: Leuprolide impurity 4
Brand: Vaqora Chemicals
SKU: VQ-048846

About Leuprolide impurity 4

Leuprolide impurity 4 (CAS 267878-61-5) is an impurity of Leuprolide offered by Vaqora Chemicals. Formula C56H79N15O10, molecular weight 1122.3 g/mol. Common synonyms include Des-Ser4-Leuprolide and (Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

This Leuprolide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Leuprolide impurity 4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Leuprolide

View every impurity, metabolite and intermediate we list for Leuprolide.

Leuprolide impurities

Specifications & identifiers

Chemical identifiers
Product name	Leuprolide impurity 4
Catalogue No.	VQ-048846
CAS Number	267878-61-5
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular formula	C₅₆H₇₉N₁₅O₁₀
Molecular weight	1122.3 g/mol
Exact mass	1121.6134
Grade	Reference Standard
HSN code	38229090
InChIKey	MMKAEZTWGFDHGK-OFHYFIBLSA-N
SMILES	CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
PubChem CID	101013241

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	13 / 12
TPSA	382 Å²
Synonyms	Des-Ser4-Leuprolide, (Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH, pE-HWY(dL)LRP-NHEt, Pyr-His-Trp-Tyr-D-Leu-Leu-Arg-Pro-NHEt, (Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH trifluoroacetate salt, (Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt 9)-LHRH trifluoroacetate salt

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leuprolide impurity 4?

The CAS Registry Number of Leuprolide impurity 4 is 267878-61-5. It is also known as Des-Ser4-Leuprolide, (Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH, pE-HWY(dL)LRP-NHEt.

What is the molecular formula and molecular weight of Leuprolide impurity 4?

Leuprolide impurity 4 has the molecular formula C56H79N15O10 and a molecular weight of 1122.3 g/mol.

What is Leuprolide impurity 4 used for?

Leuprolide impurity 4 is supplied as a characterised reference material related to Leuprolide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leuprolide impurity 4 can I order?

We supply Leuprolide impurity 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leuprolide impurity 4?

Yes. Every lot of Leuprolide impurity 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leuprolide impurity 4 be shipped internationally?

Yes. Leuprolide impurity 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.