Des-1,2,3-Leuprolide

Name: Des-1,2,3-Leuprolide
Brand: Vaqora Chemicals
SKU: VQ-037969

About Des-1,2,3-Leuprolide

Des-1,2,3-Leuprolide is an impurity of Leuprolide carrying the CAS registry number 202333-85-5. Formula C37H62N10O8, molecular weight 775.0 g/mol. Common synonyms include H-SY(dL)LRP-NHEt and H-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Leuprolide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Des-1,2,3-Leuprolide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Leuprolide

View every impurity, metabolite and intermediate we list for Leuprolide.

Leuprolide impurities

Specifications & identifiers

Chemical identifiers
Product name	Des-1,2,3-Leuprolide
Catalogue No.	VQ-037969
CAS Number	202333-85-5
IUPAC name	(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-ethylpyrrolidine-2-carboxamide
Molecular formula	C₃₇H₆₂N₁₀O₈
Molecular weight	775 g/mol
Exact mass	774.4752
Grade	Reference Standard
HSN code	38229090
InChIKey	GLCZVWJJUYVLEG-CKJBBXNYSA-N
SMILES	CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)N
PubChem CID	102602271

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	10 / 10
TPSA	297 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Des-1,2,3-Leuprolide?

The CAS Registry Number of Des-1,2,3-Leuprolide is 202333-85-5. It is also known as L-Seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide, H-SY(dL)LRP-NHEt, H-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.

What is the molecular formula and molecular weight of Des-1,2,3-Leuprolide?

Des-1,2,3-Leuprolide has the molecular formula C37H62N10O8 and a molecular weight of 775 g/mol.

What is Des-1,2,3-Leuprolide used for?

Des-1,2,3-Leuprolide is supplied as a characterised reference material related to Leuprolide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Des-1,2,3-Leuprolide can I order?

We supply Des-1,2,3-Leuprolide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Des-1,2,3-Leuprolide?

Yes. Every lot of Des-1,2,3-Leuprolide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Des-1,2,3-Leuprolide be shipped internationally?

Yes. We export Des-1,2,3-Leuprolide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.