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Pharmacopeial Impurities (EP / USP / BP)Reference Standard In stock

Levothyroxine EP Impurity A

Synonyms: 3,3',5-Triiodo-L-thyronine · O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine · (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate · (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid

CAS No.6893-02-3
FormulaC15H12I3NO4
Mol. weight650.97
Catalogue No.VQ-006468
PurityReference Standard
HSN38229090

Levothyroxine EP Impurity A (CAS 6893-02-3) – Levothyroxine impurity standard. C15H12I3NO4, MW 650.97. From Vaqora Chemicals, with COA and worldwide delivery.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
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Batch COA with every lot
16-section GHS SDS
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About Levothyroxine EP Impurity A

Listed under CAS 6893-02-3, Levothyroxine EP Impurity A is a pharmacopeial impurity of Levothyroxine available from Vaqora Chemicals. Its molecular formula is C15H12I3NO4 and its molecular weight is 650.97 g/mol. The IUPAC name is (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid. It is also known as 3,3',5-Triiodo-L-thyronine or 3,3',5-Triiodothyronine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

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Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product nameLevothyroxine EP Impurity A
Catalogue No.VQ-006468
CAS Number6893-02-3
IUPAC name(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formulaC15H12I3NO4
Molecular weight650.97 g/mol
Exact mass650.7901
GradeReference Standard
HSN code38229090
InChIKeyAUYYCJSJGJYCDS-LBPRGKRZSA-N
SMILESC1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O
PubChem CID5920
Physical properties
Physical formSolid
LogP (XLogP3)1.7
H-bond donors / acceptors3 / 5
TPSA92.8 Ų
Synonyms3,3',5-Triiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate, (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid, 3,3',5-Triiodothyronine, 3,5,3'-Triiodothyronine, 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine, Cyronine, L-Liothyronine, L-T3, L-Triiodothyronine, Liothyronin

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity A?

The CAS Registry Number of Levothyroxine EP Impurity A is 6893-02-3. It is also known as 3,3',5-Triiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity A?

Levothyroxine EP Impurity A has the molecular formula C15H12I3NO4 and a molecular weight of 650.97 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid.

What is Levothyroxine EP Impurity A used for?

Levothyroxine EP Impurity A is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity A can I order?

We supply Levothyroxine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity A?

Yes. Every lot of Levothyroxine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity A be shipped internationally?

Yes. Levothyroxine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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