Levothyroxine EP Impurity H (Stage -1)

Name: Levothyroxine EP Impurity H (Stage -1)
Brand: Vaqora Chemicals
SKU: VQ-006477

About Levothyroxine EP Impurity H (Stage -1)

Levothyroxine EP Impurity H (Stage -1) (CAS 118-97-8) is a pharmacopeial impurity of Levothyroxine offered by Vaqora Chemicals. Formula C7H3ClN2O6, molecular weight 246.56 g/mol. The IUPAC name is 4-chloro-3,5-dinitrobenzoic acid. It is also known as 3,5-Dinitro-4-chlorobenzoic acid or 4-Chloro-3,5-dinitrobenzenecarboxylic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Levothyroxine EP Impurity H (Stage -1) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity H (Stage -1)
Catalogue No.	VQ-006477
CAS Number	118-97-8
IUPAC name	4-chloro-3,5-dinitrobenzoic acid
Molecular formula	C₇H₃ClN₂O₆
Molecular weight	246.56 g/mol
Exact mass	245.968
Grade	Reference Standard
HSN code	38229090
InChIKey	PCTFIHOVQYYAMH-UHFFFAOYSA-N
SMILES	C1=C(C=C(C(=C1[N+](=O)[O-])Cl)[N+](=O)[O-])C(=O)O
PubChem CID	8377

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 6
TPSA	129 Å²
Synonyms	3,5-Dinitro-4-chlorobenzoic acid, 4-Chloro-3,5-dinitrobenzenecarboxylic acid, Levothyroxine EP Impurity H ( Stage -1), Benzoic acid, 4-chloro-3,5-dinitro-, 4-Chloro-3,5-dinitrobenzoate, Benzoicacid, 4-chloro-3,5-dinitro-, 4-chloro-3,5-dinitro-benzoic acid, 3,5-Dinitro-4-chlorobenzoicacid, Bumetanide Impurity 17, 3,5-dinitro-4-chloro-benzoic acid, 4-Chloro-3,5-dinitrobenzoic acid, 97%

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 118-97-8

4-Chloro-3,5-dinitrobenzoic acid, 97%

CAS: 118-97-8
Formula: C₇H₃ClN₂O₆
MW: 246.56 g/mol

VQ-009801

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity H (Stage -1)?

The CAS Registry Number of Levothyroxine EP Impurity H (Stage -1) is 118-97-8. It is also known as 3,5-Dinitro-4-chlorobenzoic acid, 4-Chloro-3,5-dinitrobenzenecarboxylic acid, Levothyroxine EP Impurity H ( Stage -1).

What is the molecular formula and molecular weight of Levothyroxine EP Impurity H (Stage -1)?

Levothyroxine EP Impurity H (Stage -1) has the molecular formula C7H3ClN2O6 and a molecular weight of 246.56 g/mol. Its IUPAC name is 4-chloro-3,5-dinitrobenzoic acid.

What is Levothyroxine EP Impurity H (Stage -1) used for?

Levothyroxine EP Impurity H (Stage -1) is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity H (Stage -1) can I order?

We supply Levothyroxine EP Impurity H (Stage -1) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity H (Stage -1)?

Yes. Every lot of Levothyroxine EP Impurity H (Stage -1) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity H (Stage -1) be shipped internationally?

Yes. Levothyroxine EP Impurity H (Stage -1) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.