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VAQORACHEMICALS
API ImpuritiesReference Standard In stock

Levothyroxine Impurity D (Stage-1)

Synonyms: 4-Hydroxy-3,5-dinitrobenzeneacetic acid · 3,5-Dinitro-4-hydroxybenzeneacetic acid · 3,5-Dinitro-4-hydroxyphenylacetic acid · 4-Hydroxy-3,5-dinitrophenylacetic acid

CAS No.10463-37-3
FormulaC8H6N2O7
Mol. weight242.14
Catalogue No.VQ-005187
PurityReference Standard
HSN38229090

Levothyroxine Impurity D (Stage-1) (CAS 10463-37-3) – Levothyroxine impurity standard. C8H6N2O7, MW 242.14. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available
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25 mg
50 mg
100 mg
250 mg
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16-section GHS SDS
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DG-compliant packing

About Levothyroxine Impurity D (Stage-1)

Listed under CAS 10463-37-3, Levothyroxine Impurity D (Stage-1) is an impurity of Levothyroxine available from Vaqora Chemicals. Its molecular formula is C8H6N2O7 and its molecular weight is 242.14 g/mol. Systematically, it is named 2-(4-hydroxy-3,5-dinitrophenyl)acetic acid. Common synonyms include 4-Hydroxy-3,5-dinitrobenzeneacetic acid and 3,5-Dinitro-4-hydroxybenzeneacetic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Levothyroxine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine Impurity D (Stage-1) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product nameLevothyroxine Impurity D (Stage-1)
Catalogue No.VQ-005187
CAS Number10463-37-3
IUPAC name2-(4-hydroxy-3,5-dinitrophenyl)acetic acid
Molecular formulaC8H6N2O7
Molecular weight242.14 g/mol
Exact mass242.0175
GradeReference Standard
HSN code38229090
InChIKeyMLVYQQLUGFSXQH-UHFFFAOYSA-N
SMILESC1=C(C=C(C(=C1[N+](=O)[O-])O)[N+](=O)[O-])CC(=O)O
PubChem CID98596
Physical properties
Physical formSolid
LogP (XLogP3)1.2
H-bond donors / acceptors2 / 7
TPSA149 Ų
Synonyms4-Hydroxy-3,5-dinitrobenzeneacetic acid, 3,5-Dinitro-4-hydroxybenzeneacetic acid, 3,5-Dinitro-4-hydroxyphenylacetic acid, 4-Hydroxy-3,5-dinitrophenylacetic acid, Levothyroxine Impurity D (Stage-1 ), 3,5-Dinitro-4-hydroxyphenacetic acid, 4-Hydroxy-3,5-dinitrophenacetyl, (4-Hydroxy-3,5-dinitrophenyl)acetic acid, (4-hydroxy-3,5-dinitro-phenyl)-acetic acid, Benzeneacetic acid, 4-hydroxy-3,5-dinitro-, 2-(4-hydroxy-3,5-dinitro-phenyl)acetic acid, 3,5-Dinitro-4-hydroxyphenyl-acetic acid

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Levothyroxine Impurity D (Stage-1)?

The CAS Registry Number of Levothyroxine Impurity D (Stage-1) is 10463-37-3. It is also known as 4-Hydroxy-3,5-dinitrobenzeneacetic acid, 3,5-Dinitro-4-hydroxybenzeneacetic acid, 3,5-Dinitro-4-hydroxyphenylacetic acid.

What is the molecular formula and molecular weight of Levothyroxine Impurity D (Stage-1)?

Levothyroxine Impurity D (Stage-1) has the molecular formula C8H6N2O7 and a molecular weight of 242.14 g/mol. Its IUPAC name is 2-(4-hydroxy-3,5-dinitrophenyl)acetic acid.

What is Levothyroxine Impurity D (Stage-1) used for?

Levothyroxine Impurity D (Stage-1) is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine Impurity D (Stage-1) can I order?

We supply Levothyroxine Impurity D (Stage-1) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine Impurity D (Stage-1)?

Yes. Every lot of Levothyroxine Impurity D (Stage-1) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine Impurity D (Stage-1) be shipped internationally?

Yes. Levothyroxine Impurity D (Stage-1) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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