Lofepramine Hydrochloride

Name: Lofepramine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-038098

About Lofepramine Hydrochloride

Lofepramine Hydrochloride is a high-purity reference standard of Lofepramine carrying the CAS registry number 26786-32-3. With the molecular formula C26H28Cl2N2O, it has a molar mass of 455.4 g/mol. It is also known as Lofepramine HCl or Clopepramine hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Lofepramine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lofepramine

View every impurity, metabolite and intermediate we list for Lofepramine.

Lofepramine impurities

Specifications & identifiers

Chemical identifiers
Product name	Lofepramine Hydrochloride
Catalogue No.	VQ-038098
CAS Number	26786-32-3
IUPAC name	1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone;hydrochloride
Molecular formula	C₂₆H₂₈Cl₂N₂O
Molecular weight	455.4 g/mol
Exact mass	454.1579
Grade	Reference Standard
HSN code	38229090
InChIKey	ZWZIQPOLMDPIQM-UHFFFAOYSA-N
SMILES	CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl.Cl
PubChem CID	33611

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	23.6 Å²
Synonyms	Lofepramine HCl, Clopepramine hydrochloride, WHR-2908A, Hydrochloride, Lofepramine, Lopramine (hydrochloride), Iopramine hydrochloride, WHR 2908A, 5H-Dibenz(b,f)azepine, 5-(3-((p-chlorobenzoylmethyl)-N-methylamino)propyl)-, hydrochloride, N-Methyl-N-(4'-chlorophenacyl)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)propylamine HCl, Lofepramine Hydrochloride (Form A)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P270, P271, P273, P301 + P317, P304 + P340, P319, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lofepramine Hydrochloride?

The CAS Registry Number of Lofepramine Hydrochloride is 26786-32-3. It is also known as Lofepramine HCl, Clopepramine hydrochloride, WHR-2908A.

What is the molecular formula and molecular weight of Lofepramine Hydrochloride?

Lofepramine Hydrochloride has the molecular formula C26H28Cl2N2O and a molecular weight of 455.4 g/mol.

What is Lofepramine Hydrochloride used for?

Lofepramine Hydrochloride is supplied as a characterised reference material related to Lofepramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lofepramine Hydrochloride can I order?

We supply Lofepramine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lofepramine Hydrochloride?

Yes. Every lot of Lofepramine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lofepramine Hydrochloride be shipped internationally?

Yes. Lofepramine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.