Loperamide EP Impurity F

Name: Loperamide EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-022999

About Loperamide EP Impurity F

Loperamide EP Impurity F (CAS 106900-12-3) is a pharmacopeial impurity of Loperamide offered by Vaqora Chemicals. Its molecular formula is C29H33ClN2O3 and its molecular weight is 493.0 g/mol. Its systematic (IUPAC) name is 4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide. Common synonyms include Loperamide N-oxide and Loperamide Hydrochloride - Impurity F.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Loperamide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Loperamide EP Impurity F is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loperamide EP Impurity F
Catalogue No.	VQ-022999
CAS Number	106900-12-3
IUPAC name	4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
Molecular formula	C₂₉H₃₃ClN₂O₃
Molecular weight	493 g/mol
Exact mass	492.218
Grade	Reference Standard
HSN code	38229090
InChIKey	KXVSBTJVTUVNPM-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C(CC[N+]1(CCC(CC1)(C2=CC=C(C=C2)Cl)O)[O-])(C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID	71421

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	1 / 3
TPSA	58.6 Å²
Synonyms	Loperamide N-oxide, Loperamide Hydrochloride - Impurity F, Loperamide Trans-N-Oxide, Loperamide oxide, trans-Loperamide N-Oxide, Arestal, Loperamide oxyde, Loperamide oxide anhydrous, Oxido de loperamida, Loperamide oxide anhydrous, cis-, Loperamidum oxidum, trans-N-Oxide of loperamide

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loperamide EP Impurity F?

The CAS Registry Number of Loperamide EP Impurity F is 106900-12-3. It is also known as Loperamide N-oxide, Loperamide Hydrochloride - Impurity F, Loperamide Trans-N-Oxide.

What is the molecular formula and molecular weight of Loperamide EP Impurity F?

Loperamide EP Impurity F has the molecular formula C29H33ClN2O3 and a molecular weight of 493 g/mol. Its IUPAC name is 4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide.

What is Loperamide EP Impurity F used for?

Loperamide EP Impurity F is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide EP Impurity F can I order?

We supply Loperamide EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide EP Impurity F?

Yes. Every lot of Loperamide EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide EP Impurity F be shipped internationally?

Yes. Loperamide EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.