Loxapine

Name: Loxapine
Brand: Vaqora Chemicals
SKU: VQ-048966

About Loxapine

Listed under CAS 1977-10-2, Loxapine is a high-purity reference standard of Loxapine available from Vaqora Chemicals. With the molecular formula C18H18ClN3O, it has a molar mass of 327.8 g/mol. The IUPAC name is 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine. It is also known as Cloxazepine or Oxilapine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

As a reference sample of Loxapine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Loxapine

View every impurity, metabolite and intermediate we list for Loxapine.

Loxapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Loxapine
Catalogue No.	VQ-048966
CAS Number	1977-10-2
IUPAC name	8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Molecular formula	C₁₈H₁₈ClN₃O
Molecular weight	327.8 g/mol
Exact mass	327.1138
Grade	Reference Standard
HSN code	38229090
InChIKey	XJGVXQDUIWGIRW-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
PubChem CID	3964

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	28.1 Å²
Synonyms	Cloxazepine, Oxilapine, Loxapin, Hydrofluoride 3170, SUM 3170, SUM-3170, Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine, Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzoxazepine

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loxapine?

The CAS Registry Number of Loxapine is 1977-10-2. It is also known as Cloxazepine, Oxilapine, Loxapin.

What is the molecular formula and molecular weight of Loxapine?

Loxapine has the molecular formula C18H18ClN3O and a molecular weight of 327.8 g/mol. Its IUPAC name is 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine.

What is Loxapine used for?

Loxapine is supplied as a characterised reference material related to Loxapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loxapine can I order?

We supply Loxapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loxapine?

Yes. Every lot of Loxapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loxapine be shipped internationally?

Yes. Loxapine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.