Lumacaftor-d4

Name: Lumacaftor-d4
Brand: Vaqora Chemicals
SKU: VQ-038188

About Lumacaftor-d4

Vaqora Chemicals supplies Lumacaftor-d4, a stable isotope labelled analogue related to Lumacaftor registered under CAS number 2733561-44-7. With the molecular formula C24H18F2N2O5, it has a molar mass of 456.4 g/mol. It is also known as VX 809-d4 or Lumacaftor-d4 (VX-809-d4).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Lumacaftor and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Lumacaftor-d4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Lumacaftor

View every impurity, metabolite and intermediate we list for Lumacaftor.

Lumacaftor impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Lumacaftor-d4
Catalogue No.	VQ-038188
CAS Number	2733561-44-7
IUPAC name	3-[3-methyl-6-[[2,2,3,3-tetradeuterio-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-2-pyridinyl]benzoic acid
Molecular formula	C₂₄H₁₈F₂N₂O₅
Molecular weight	456.4 g/mol
Exact mass	456.1435
Grade	Reference Standard
HSN code	38229090
InChIKey	UFSKUSARDNFIRC-YQUBHJMPSA-N
SMILES	[2H]C1(C(C1(C2=CC3=C(C=C2)OC(O3)(F)F)C(=O)NC4=NC(=C(C=C4)C)C5=CC(=CC=C5)C(=O)O)([2H])[2H])[2H]
PubChem CID	166642625

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 8
TPSA	97.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lumacaftor-d4?

The CAS Registry Number of Lumacaftor-d4 is 2733561-44-7. It is also known as VX 809-d4, Lumacaftor-d4 (VX-809-d4).

What is the molecular formula and molecular weight of Lumacaftor-d4?

Lumacaftor-d4 has the molecular formula C24H18F2N2O5 and a molecular weight of 456.4 g/mol. Its IUPAC name is 3-[3-methyl-6-[[2,2,3,3-tetradeuterio-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-2-pyridinyl]benzoic acid.

What is Lumacaftor-d4 used for?

Lumacaftor-d4 is supplied as a characterised reference material related to Lumacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lumacaftor-d4 can I order?

We supply Lumacaftor-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lumacaftor-d4?

Yes. Every lot of Lumacaftor-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lumacaftor-d4 be shipped internationally?

Yes. We export Lumacaftor-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.