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VAQORACHEMICALS
API ImpuritiesReference StandardAvailable on request

Maytansinoid DM 4

Synonyms: Ravtansine · N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine · N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine · N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxo-2-sulfopentyl]-N2'-deacetylmaytansine

CAS No.796073-69-3
FormulaC38H54ClN3O10S
Mol. weight780.40
Catalogue No.VQ-038314
PurityReference Standard
HSN38229090

Maytansinoid DM 4 (CAS 796073-69-3) – Mertansine impurity standard. C38H54ClN3O10S, MW 780.4. COA included. Worldwide shipping from Vaqora Chemicals.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Maytansinoid DM 4

Maytansinoid DM 4 (CAS 796073-69-3) is an impurity of Mertansine offered by Vaqora Chemicals. Formula C38H54ClN3O10S, molecular weight 780.4 g/mol. It is also known as Ravtansine or DM 4.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Mertansine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Mertansine

View every impurity, metabolite and intermediate we list for Mertansine.

Mertansine impurities

Specifications & identifiers

Chemical identifiers
Product nameMaytansinoid DM 4
Catalogue No.VQ-038314
CAS Number796073-69-3
IUPAC name[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl-(4-methyl-4-sulfanylpentanoyl)amino]propanoate
Molecular formulaC38H54ClN3O10S
Molecular weight780.4 g/mol
Exact mass779.3218
GradeReference Standard
HSN code38229090
InChIKeyJFCFGYGEYRIEBE-YVLHJLIDSA-N
SMILESC[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)S)C)\C)OC)(NC(=O)O2)O
PubChem CID11686439
Physical properties
Physical formSolid
LogP (XLogP3)3.2
H-bond donors / acceptors3 / 11
TPSA157 Ų
SynonymsRavtansine, N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine, N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine, N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxo-2-sulfopentyl]-N2'-deacetylmaytansine, DM 4, DM-4, EX-A3441, Maytansine, N2a(2)-deacetyl-N2a(2)-(4-mercapto-4-methyl-1-oxopentyl)-

Safety & hazard information (GHS)

GHS05 Corrosive
Corrosive
GHS06 Toxic
Toxic
GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Danger

Hazard statements

  • H300Fatal if swallowed
  • H301Toxic if swallowed
  • H310Fatal in contact with skin
  • H311Toxic in contact with skin
  • H314Causes severe skin burns and eye damage
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H331Toxic if inhaled
  • H340May cause genetic defects
  • H341Suspected of causing genetic defects
  • H360May damage fertility or the unborn child
  • H361Suspected of damaging fertility or the unborn child
  • H370Causes damage to organs
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P308 + P316, P316, P318, P319, P321, P330, P332 + P317, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Maytansinoid DM 4?

The CAS Registry Number of Maytansinoid DM 4 is 796073-69-3. It is also known as Ravtansine, N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine, N2'-(4-((3-carboxypropyl)dithio)-4-methyl-1-oxo-2-sulfopentyl)-N2'-deacetylmaytansine.

What is the molecular formula and molecular weight of Maytansinoid DM 4?

Maytansinoid DM 4 has the molecular formula C38H54ClN3O10S and a molecular weight of 780.4 g/mol.

What is Maytansinoid DM 4 used for?

Maytansinoid DM 4 is supplied as a characterised reference material related to Mertansine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Maytansinoid DM 4 can I order?

We supply Maytansinoid DM 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Maytansinoid DM 4?

Yes. Every lot of Maytansinoid DM 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Maytansinoid DM 4 be shipped internationally?

Yes. Maytansinoid DM 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Maytansinoid DM 4

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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