Medroxyprogesterone Acetate EP Impurity B

Name: Medroxyprogesterone Acetate EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-026585

About Medroxyprogesterone Acetate EP Impurity B

Medroxyprogesterone Acetate EP Impurity B (CAS 520-85-4) is a pharmacopeial impurity of Medroxyprogesterone offered by Vaqora Chemicals. Its molecular formula is C22H32O3 and its molecular weight is 344.5 g/mol. Alternative names: Medroxyprogesterone and Medroxyprogesterone Acetate - Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Medroxyprogesterone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Medroxyprogesterone Acetate EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Medroxyprogesterone

View every impurity, metabolite and intermediate we list for Medroxyprogesterone.

Medroxyprogesterone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Medroxyprogesterone Acetate EP Impurity B
Catalogue No.	VQ-026585
CAS Number	520-85-4
IUPAC name	(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₂O₃
Molecular weight	344.5 g/mol
Exact mass	344.2351
Grade	Reference Standard
HSN code	38229090
InChIKey	FRQMUZJSZHZSGN-HBNHAYAOSA-N
SMILES	C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C
PubChem CID	10631

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²
Synonyms	Medroxyprogesterone, Medroxyprogesterone (Medroxyprogesterone EP Impurity B), Medroxyprogesterone Acetate - Impurity B, Medrossiprogesterone, 6alpha-Methyl-17alpha-hydroxyprogesterone, 17-Hydroxy-6alpha-methylprogesterone, 17alpha-Hydroxy-6alpha-methylprogesterone, Farlutal inyectable, 6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione, 17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione, (6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Medroxyprogesterone Acetate EP Impurity B?

The CAS Registry Number of Medroxyprogesterone Acetate EP Impurity B is 520-85-4. It is also known as Medroxyprogesterone, Medroxyprogesterone (Medroxyprogesterone EP Impurity B), Medroxyprogesterone Acetate - Impurity B.

What is the molecular formula and molecular weight of Medroxyprogesterone Acetate EP Impurity B?

Medroxyprogesterone Acetate EP Impurity B has the molecular formula C22H32O3 and a molecular weight of 344.5 g/mol. Its IUPAC name is (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is Medroxyprogesterone Acetate EP Impurity B used for?

Medroxyprogesterone Acetate EP Impurity B is supplied as a characterised reference material related to Medroxyprogesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Medroxyprogesterone Acetate EP Impurity B can I order?

We supply Medroxyprogesterone Acetate EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Medroxyprogesterone Acetate EP Impurity B?

Yes. Every lot of Medroxyprogesterone Acetate EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Medroxyprogesterone Acetate EP Impurity B be shipped internationally?

Yes. Medroxyprogesterone Acetate EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.