Mefloquine EP Impurity B

Name: Mefloquine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-006498

About Mefloquine EP Impurity B

Mefloquine EP Impurity B is a pharmacopeial impurity of Mefloquine carrying the CAS registry number 68496-04-8. Its molecular formula is C17H10F6N2O and its molecular weight is 372.26 g/mol. The IUPAC name is [2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanol. Common synonyms include MQ-IS and Dehydro Mefloquine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Mefloquine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Mefloquine

View every impurity, metabolite and intermediate we list for Mefloquine.

Mefloquine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Mefloquine EP Impurity B
Catalogue No.	VQ-006498
CAS Number	68496-04-8
IUPAC name	[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanol
Molecular formula	C₁₇H₁₀F₆N₂O
Molecular weight	372.26 g/mol
Exact mass	372.0697
Grade	Reference Standard
HSN code	38229090
InChIKey	LUDFDSXDVJABBT-UHFFFAOYSA-N
SMILES	C1=CC=NC(=C1)C(C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O
PubChem CID	129617

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 9
TPSA	46 Å²
Synonyms	(RS)-[2,8-Bis(trifluoromethyl)quinolin-4-yl](pyridin-2-yl)methanol, (2,8-Bis-trifluoromethyl-quinolin-4-yl)-pyridin-2-yl-methanol, α-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol, MQ-IS, alpha-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol, 4-Quinolinemethanol, alpha-2-pyridinyl-2,8-bis(trifluoromethyl)-, Dehydro Mefloquine, (2,8-Bis(trifluoromethyl)quinolin-4-yl)(pyridin-2-yl)methanol, 2,8-Bis[trifluoromethyl]-a-(2-pyridyl)-4-quinolinemethanol, [2,8-bis(trifluoromethyl)-4-quinolyl]-(2-pyridyl)methanol, [2,8-Bis(trifluoromethyl)-4-quinolinyl](2-pyridinyl)methanol #, (2,8-Bis-trifluoromethyl-quinolin-4-yl)-pyridin-2-yl-methanol, AldrichCPR

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P270, P273, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Mefloquine EP Impurity B?

The CAS Registry Number of Mefloquine EP Impurity B is 68496-04-8. It is also known as (RS)-[2,8-Bis(trifluoromethyl)quinolin-4-yl](pyridin-2-yl)methanol, (2,8-Bis-trifluoromethyl-quinolin-4-yl)-pyridin-2-yl-methanol, α-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol.

What is the molecular formula and molecular weight of Mefloquine EP Impurity B?

Mefloquine EP Impurity B has the molecular formula C17H10F6N2O and a molecular weight of 372.26 g/mol. Its IUPAC name is [2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanol.

What is Mefloquine EP Impurity B used for?

Mefloquine EP Impurity B is supplied as a characterised reference material related to Mefloquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Mefloquine EP Impurity B can I order?

We supply Mefloquine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Mefloquine EP Impurity B?

Yes. Every lot of Mefloquine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Mefloquine EP Impurity B be shipped internationally?

Yes. Mefloquine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.