Megestrol Acetate EP Impurity K

Name: Megestrol Acetate EP Impurity K
Brand: Vaqora Chemicals
SKU: VQ-021270

About Megestrol Acetate EP Impurity K

Listed under CAS 302-23-8, Megestrol Acetate EP Impurity K is a pharmacopeial impurity of Megestrol available from Vaqora Chemicals. With the molecular formula C23H32O4, it has a molar mass of 372.5 g/mol. Alternative names: Hydroxyprogesterone Acetate and 17-Alpha-Acetoxy Progesterone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Megestrol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Megestrol Acetate EP Impurity K in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Megestrol

View every impurity, metabolite and intermediate we list for Megestrol.

Megestrol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Megestrol Acetate EP Impurity K
Catalogue No.	VQ-021270
CAS Number	302-23-8
IUPAC name	[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₃H₃₂O₄
Molecular weight	372.5 g/mol
Exact mass	372.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	VTHUYJIXSMGYOQ-KOORYGTMSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)OC(=O)C
PubChem CID	10156152

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 4
TPSA	60.4 Å²
Synonyms	Hydroxyprogesterone Acetate, 17-Alpha-Acetoxy Progesterone, Medroxyprogesterone Acetate - Impurity H, Chlormadinone Acetate EP Impurity G, Medroxyprogesterone EP Impurity H, Megestrol Acetate - Impurity K, Chlormadinone Acetate - Impurity G, 17alpha-Acetoxyprogesterone, Prodox acetate, Acetoxyprogesterone, 17-Hydroxypregn-4-ene-3,20-dione acetate, Pregn-4-ene-3,20-dione, 17-(acetyloxy)-

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Megestrol Acetate EP Impurity K?

The CAS Registry Number of Megestrol Acetate EP Impurity K is 302-23-8. It is also known as Hydroxyprogesterone Acetate, 17-Alpha-Acetoxy Progesterone, Medroxyprogesterone Acetate - Impurity H.

What is the molecular formula and molecular weight of Megestrol Acetate EP Impurity K?

Megestrol Acetate EP Impurity K has the molecular formula C23H32O4 and a molecular weight of 372.5 g/mol. Its IUPAC name is [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate.

What is Megestrol Acetate EP Impurity K used for?

Megestrol Acetate EP Impurity K is supplied as a characterised reference material related to Megestrol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Megestrol Acetate EP Impurity K can I order?

We supply Megestrol Acetate EP Impurity K in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Megestrol Acetate EP Impurity K?

Yes. Every lot of Megestrol Acetate EP Impurity K is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Megestrol Acetate EP Impurity K be shipped internationally?

Yes. Megestrol Acetate EP Impurity K is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.