Methacycline Hydrochloride

Name: Methacycline Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-021207

About Methacycline Hydrochloride

Vaqora Chemicals supplies Methacycline Hydrochloride, an impurity of Doxycycline registered under CAS number 3963-95-9. Formula C22H23ClN2O8, molecular weight 478.9 g/mol. Common synonyms include Methacycline HCl and Ciclobiotic.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Doxycycline to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Methacycline Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Doxycycline

View every impurity, metabolite and intermediate we list for Doxycycline.

Doxycycline impurities

Specifications & identifiers

Chemical identifiers
Product name	Methacycline Hydrochloride
Catalogue No.	VQ-021207
CAS Number	3963-95-9
IUPAC name	(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
Molecular formula	C₂₂H₂₃ClN₂O₈
Molecular weight	478.9 g/mol
Exact mass	478.1143
Grade	Reference Standard
HSN code	38229090
InChIKey	VXPSARQTYDZXAO-CCHMMTNSSA-N
SMILES	CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O.Cl
PubChem CID	54685047

Physical properties
Physical form	Solid
H-bond donors / acceptors	7 / 9
TPSA	182 Å²
Synonyms	Methacycline HCl, Ciclobiotic, Germiciclin, Metilenbiotic, Megamycine, Optimycin, Londomycin, Metacycline hydrochloride, Rondomycin, Physiomycine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methacycline Hydrochloride?

The CAS Registry Number of Methacycline Hydrochloride is 3963-95-9. It is also known as Methacycline HCl, Ciclobiotic, Germiciclin.

What is the molecular formula and molecular weight of Methacycline Hydrochloride?

Methacycline Hydrochloride has the molecular formula C22H23ClN2O8 and a molecular weight of 478.9 g/mol.

What is Methacycline Hydrochloride used for?

Methacycline Hydrochloride is supplied as a characterised reference material related to Doxycycline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methacycline Hydrochloride can I order?

We supply Methacycline Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methacycline Hydrochloride?

Yes. Every lot of Methacycline Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methacycline Hydrochloride be shipped internationally?

Yes. Methacycline Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.