Doxycycline EP Impurity E

Name: Doxycycline EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022446

About Doxycycline EP Impurity E

Vaqora Chemicals supplies Doxycycline EP Impurity E, a pharmacopeial impurity of Doxycycline registered under CAS number 79-57-2. Its molecular formula is C22H24N2O9 and its molecular weight is 460.4 g/mol. Common synonyms include Oxytetracycline and Doxycycline Hyclate - Impurity E.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Doxycycline, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxycycline

View every impurity, metabolite and intermediate we list for Doxycycline.

Doxycycline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Doxycycline EP Impurity E
Catalogue No.	VQ-022446
CAS Number	79-57-2
IUPAC name	(4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Molecular formula	C₂₂H₂₄N₂O₉
Molecular weight	460.4 g/mol
Exact mass	460.1482
Grade	Reference Standard
HSN code	38229090
InChIKey	OWFJMIVZYSDULZ-PXOLEDIWSA-N
SMILES	C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
PubChem CID	54675779

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.6
H-bond donors / acceptors	7 / 10
TPSA	202 Å²
Synonyms	Oxytetracycline, Doxycycline Hyclate - Impurity E, Terramycin, Oxymycin, Oxytetracyclin, Oxyterracine, Ryomycin, Oxitetracyclin, Terramitsin, Adamycin, Riomitsin, Oxytetracycline (anhydrous)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H410Very toxic to aquatic life with long lasting effects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxycycline EP Impurity E?

The CAS Registry Number of Doxycycline EP Impurity E is 79-57-2. It is also known as Oxytetracycline, Doxycycline Hyclate - Impurity E, Terramycin.

What is the molecular formula and molecular weight of Doxycycline EP Impurity E?

Doxycycline EP Impurity E has the molecular formula C22H24N2O9 and a molecular weight of 460.4 g/mol. Its IUPAC name is (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide.

What is Doxycycline EP Impurity E used for?

Doxycycline EP Impurity E is supplied as a characterised reference material related to Doxycycline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxycycline EP Impurity E can I order?

We supply Doxycycline EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxycycline EP Impurity E?

Yes. Every lot of Doxycycline EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxycycline EP Impurity E be shipped internationally?

Yes. Doxycycline EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.