Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-c… 28535-81-1

Name: Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate
Brand: Vaqora Chemicals
SKU: VQ-049729

About Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate

Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate (CAS 28535-81-1) is a process intermediate or related compound of Estradiol offered by Vaqora Chemicals. The compound has the formula C29H44O7, corresponding to a molecular weight of 504.7 g/mol. It is also known as Methyl 3|A,7|A-Diacetoxy-12-Oxo-5|A-Cholanate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Estradiol, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate
Catalogue No.	VQ-049729
CAS Number	28535-81-1
IUPAC name	methyl (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-diacetyloxy-10,13-dimethyl-12-oxo-1,2,3,4,5,6,7,8,9,11,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoate
Molecular formula	C₂₉H₄₄O₇
Molecular weight	504.7 g/mol
Exact mass	504.3087
InChIKey	GVIZCQOBODPSLY-ZNYVGMLLSA-N
SMILES	C[C@H](CCC(=O)OC)[C@H]1CC[C@@H]2[C@@]1(C(=O)C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)OC(=O)C)C)OC(=O)C)C
PubChem CID	10553555

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	0 / 7
TPSA	96 Å²
Synonyms	Methyl 3alpha,7alpha-diacetoxy-12-oxo-5beta-cholanate, Methyl 3a,7a-Diacetoxy-12-oxo-5b-cholan-24-oate, Methyl 3, A,7, A-Diacetoxy-12-Oxo-5, A-Cholanate, Methyl 3alpha,7alpha-bis(acetyloxy)-12-oxo-5beta-cholan-24-oate, Methyl 3I+/-lpha,7alpha-diacetoxy-12-oxo-5beta-cholan-24-oate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate?

The CAS Registry Number of Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate is 28535-81-1. It is also known as Methyl 3alpha,7alpha-diacetoxy-12-oxo-5beta-cholanate, Methyl 3a,7a-Diacetoxy-12-oxo-5b-cholan-24-oate, Methyl 3.

What is the molecular formula and molecular weight of Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate?

Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate has the molecular formula C29H44O7 and a molecular weight of 504.7 g/mol.

What is Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate used for?

Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate can I order?

We supply Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate?

Yes. Every lot of Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate be shipped internationally?

Yes. Methyl 3alpha,7alpha-Diacetoxy-12-oxo-5beta-cholan-24-oate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.