Methylpropylnitrosamine

Name: Methylpropylnitrosamine
Brand: Vaqora Chemicals
SKU: VQ-028624

About Methylpropylnitrosamine

Listed under CAS 924-46-9, Methylpropylnitrosamine is a nitrosamine impurity of Valsartan available from Vaqora Chemicals. The compound has the formula C4H10N2O, corresponding to a molecular weight of 102.14 g/mol. Its systematic (IUPAC) name is N-methyl-N-propylnitrous amide. Common synonyms include Nitrosomethylpropylamine and Methylpropylnitrosamine (Mix of isomers).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Methylpropylnitrosamine
Catalogue No.	VQ-028624
CAS Number	924-46-9
IUPAC name	N-methyl-N-propylnitrous amide
Molecular formula	C₄H₁₀N₂O
Molecular weight	102.14 g/mol
Exact mass	102.0793
Grade	Reference Standard
HSN code	38229090
InChIKey	ITBDKUCVKYSWMF-UHFFFAOYSA-N
SMILES	CCCN(C)N=O
PubChem CID	13545

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 3
TPSA	32.7 Å²
Synonyms	Nitrosomethylpropylamine, Methylpropylnitrosamine (Mix of isomers), Methylpropylnitrosoamine, N-Methyl-N-nitroso-1-propanamine, N-Nitrosomethyl-N-propylamine, methyl(nitroso)propylamine, N-Methyl-N-propylnitrosamine, 1-Propanamine, N-methyl-N-nitroso-, Methyl-n-propylnitrosamine, Nitrosomethyl-n-propylamine, N-Methyl-N-nitrosopropylamine, N-Nitroso methyl propylamine

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H350May cause cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methylpropylnitrosamine?

The CAS Registry Number of Methylpropylnitrosamine is 924-46-9. It is also known as Nitrosomethylpropylamine, Methylpropylnitrosamine (Mix of isomers), Methylpropylnitrosoamine.

What is the molecular formula and molecular weight of Methylpropylnitrosamine?

Methylpropylnitrosamine has the molecular formula C4H10N2O and a molecular weight of 102.14 g/mol. Its IUPAC name is N-methyl-N-propylnitrous amide.

What is Methylpropylnitrosamine used for?

Methylpropylnitrosamine is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methylpropylnitrosamine can I order?

We supply Methylpropylnitrosamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methylpropylnitrosamine?

Yes. Every lot of Methylpropylnitrosamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methylpropylnitrosamine be shipped internationally?

Yes. Methylpropylnitrosamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.