N-Nitroso-N-ethylbutylamine

Name: N-Nitroso-N-ethylbutylamine
Brand: Vaqora Chemicals
SKU: VQ-028625

About N-Nitroso-N-ethylbutylamine

Listed under CAS 4549-44-4, N-Nitroso-N-ethylbutylamine is a nitrosamine impurity of Valsartan available from Vaqora Chemicals. The compound has the formula C6H14N2O, corresponding to a molecular weight of 130.19 g/mol. Systematically, it is named N-butyl-N-ethylnitrous amide. Alternative names: N-Nitroso-N-ethylbutylamine (NEBA) and N-Nitroso ethyl butyl amine (NEBA).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Valsartan, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-N-ethylbutylamine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-N-ethylbutylamine
Catalogue No.	VQ-028625
CAS Number	4549-44-4
IUPAC name	N-butyl-N-ethylnitrous amide
Molecular formula	C₆H₁₄N₂O
Molecular weight	130.19 g/mol
Exact mass	130.1106
Grade	Reference Standard
HSN code	38229090
InChIKey	ZGMCNGHHUQZNIH-UHFFFAOYSA-N
SMILES	CCCCN(CC)N=O
PubChem CID	20680

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 3
TPSA	32.7 Å²
Synonyms	N-Nitroso-N-ethylbutylamine (NEBA), N-Nitroso ethyl butyl amine (NEBA), Ethylbutylnitrosamine, Ethyl-N-butylnitrosamine, N-Ethyl-N-butylnitrosamine, N-Nitroso-N-butylethylamine, Butanamine, N-ethyl-N-nitroso-, Butylamine, N-ethyl-N-nitroso-, N-Ethyl-N-nitrosobutylamine, Nitrosoethylbutylamine, 1-Butanamine, N-ethyl-N-nitroso-, N-Nitrosoethyl-N-butylamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-N-ethylbutylamine?

The CAS Registry Number of N-Nitroso-N-ethylbutylamine is 4549-44-4. It is also known as N-Nitroso-N-ethylbutylamine (NEBA), N-Nitroso ethyl butyl amine (NEBA), Ethylbutylnitrosamine.

What is the molecular formula and molecular weight of N-Nitroso-N-ethylbutylamine?

N-Nitroso-N-ethylbutylamine has the molecular formula C6H14N2O and a molecular weight of 130.19 g/mol. Its IUPAC name is N-butyl-N-ethylnitrous amide.

What is N-Nitroso-N-ethylbutylamine used for?

N-Nitroso-N-ethylbutylamine is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-N-ethylbutylamine can I order?

We supply N-Nitroso-N-ethylbutylamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-N-ethylbutylamine?

Yes. Every lot of N-Nitroso-N-ethylbutylamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-N-ethylbutylamine be shipped internationally?

Yes. N-Nitroso-N-ethylbutylamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.