Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoi… 1438271-13-6

Name: Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-038651

About Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Listed under CAS 1438271-13-6, Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an impurity of Nintedanib available from Vaqora Chemicals. Formula C18H15NO4, molecular weight 309.3 g/mol. Systematically, it is named methyl (3Z)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate. Common synonyms include Methyl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Nintedanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.	VQ-038651
CAS Number	1438271-13-6
IUPAC name	methyl (3Z)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate
Molecular formula	C₁₈H₁₅NO₄
Molecular weight	309.3 g/mol
Exact mass	309.1001
Grade	Reference Standard
HSN code	38229090
InChIKey	WUVZENIISJMEHI-NXVVXOECSA-N
SMILES	CO/C(=C\1/C2=C(C=C(C=C2)C(=O)OC)NC1=O)/C3=CC=CC=C3
PubChem CID	90209517

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 4
TPSA	64.6 Å²
Synonyms	Methyl, 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester, Methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, (Z)-Methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, methyl 3-[methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate, (Z)-Methyl3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, (3z)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1h-indole-6-carboxylic acid methyl ester, Methyl (3Z)-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

The CAS Registry Number of Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is 1438271-13-6. It is also known as Methyl, 2,3-Dihydro-3-(MethoxyphenylMethylene)-2-oxo-1H-indole-6-carboxylic acid Methyl ester, Methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate.

What is the molecular formula and molecular weight of Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate has the molecular formula C18H15NO4 and a molecular weight of 309.3 g/mol. Its IUPAC name is methyl (3Z)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate.

What is Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate used for?

Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate can I order?

We supply Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

Yes. Every lot of Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate be shipped internationally?

Yes. We export Methyl(Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.