Metoprolol EP Impurity H

Name: Metoprolol EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-021814

About Metoprolol EP Impurity H

Vaqora Chemicals supplies Metoprolol EP Impurity H, a pharmacopeial impurity of Betaxolol registered under CAS number 62572-94-5. The compound has the formula C14H23NO3, corresponding to a molecular weight of 253.34 g/mol. Its systematic (IUPAC) name is 1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol. Alternative names: Betaxolol EP Impurity B and Betaxolol EP Impurity B (Free Base).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Betaxolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Betaxolol

View every impurity, metabolite and intermediate we list for Betaxolol.

Betaxolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Metoprolol EP Impurity H
Catalogue No.	VQ-021814
CAS Number	62572-94-5
IUPAC name	1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Molecular formula	C₁₄H₂₃NO₃
Molecular weight	253.34 g/mol
Exact mass	253.1678
Grade	Reference Standard
HSN code	38229090
InChIKey	CUKXSBOAIJILRY-UHFFFAOYSA-N
SMILES	CC(C)NCC(COC1=CC=C(C=C1)CCO)O
PubChem CID	162181

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 4
TPSA	61.7 Å²
Synonyms	Betaxolol EP Impurity B, Betaxolol EP Impurity B (Free Base), Betaxolol Hydrochloride - Impurity B, Metoprolol Succinate - Impurity H, Metoprolol Tartrate - Impurity H, O-Demethylmetoprolol, Benzeneethanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, O-Desmethyl Metoprolol, O-DesmethylMetoprolol, 1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol, 1-[4-(2-Hydroxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol, (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metoprolol EP Impurity H?

The CAS Registry Number of Metoprolol EP Impurity H is 62572-94-5. It is also known as Betaxolol EP Impurity B, Betaxolol EP Impurity B (Free Base), Betaxolol Hydrochloride - Impurity B.

What is the molecular formula and molecular weight of Metoprolol EP Impurity H?

Metoprolol EP Impurity H has the molecular formula C14H23NO3 and a molecular weight of 253.34 g/mol. Its IUPAC name is 1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol.

What is Metoprolol EP Impurity H used for?

Metoprolol EP Impurity H is supplied as a characterised reference material related to Betaxolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metoprolol EP Impurity H can I order?

We supply Metoprolol EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metoprolol EP Impurity H?

Yes. Every lot of Metoprolol EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metoprolol EP Impurity H be shipped internationally?

Yes. Metoprolol EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.