Midazolam - Impurity I | CAS 59467-69-5

Name: Midazolam - Impurity I
Brand: Vaqora Chemicals
SKU: VQ-044847

About Midazolam - Impurity I

Midazolam - Impurity I (CAS 59467-69-5) is an impurity of Midazolam offered by Vaqora Chemicals. The compound has the formula C18H15ClFN3, corresponding to a molecular weight of 327.8 g/mol. Its systematic (IUPAC) name is 8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine. Alternative names: Midazolam EP Impurity I.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Midazolam, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Midazolam - Impurity I is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Specifications & identifiers

Chemical identifiers
Product name	Midazolam - Impurity I
Catalogue No.	VQ-044847
CAS Number	59467-69-5
IUPAC name	8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine
Molecular formula	C₁₈H₁₅ClFN₃
Molecular weight	327.8 g/mol
Exact mass	327.0939
Grade	Reference Standard
HSN code	38229090
InChIKey	UUGUSEWJNOCDEF-UHFFFAOYSA-N
SMILES	CC1=NCC2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
PubChem CID	11023909

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 3
TPSA	28 Å²
Synonyms	Midazolam EP Impurity I, 8-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-imidazo(1,5-a)(1,4)benzodiazepine, 8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine, 8-Chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3H-imidazo[1,5-a][1,4]benzo-diazepine, 3H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midazolam - Impurity I?

The CAS Registry Number of Midazolam - Impurity I is 59467-69-5. It is also known as Midazolam EP Impurity I, 8-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-imidazo(1,5-a)(1,4)benzodiazepine, 8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine.

What is the molecular formula and molecular weight of Midazolam - Impurity I?

Midazolam - Impurity I has the molecular formula C18H15ClFN3 and a molecular weight of 327.8 g/mol. Its IUPAC name is 8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine.

What is Midazolam - Impurity I used for?

Midazolam - Impurity I is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midazolam - Impurity I can I order?

We supply Midazolam - Impurity I in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midazolam - Impurity I?

Yes. Every lot of Midazolam - Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midazolam - Impurity I be shipped internationally?

Yes. We export Midazolam - Impurity I worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.