N-Nitroso Midazolam EP Impurity A

Name: N-Nitroso Midazolam EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-044844

About N-Nitroso Midazolam EP Impurity A

Listed under CAS 59469-02-2, N-Nitroso Midazolam EP Impurity A is a nitrosamine impurity of Midazolam available from Vaqora Chemicals. With the molecular formula C18H14ClFN4O, it has a molar mass of 356.8 g/mol. Systematically, it is named 8-chloro-6-(2-fluorophenyl)-1-methyl-5-nitroso-4,6-dihydroimidazo[1,5-a][1,4]benzodiazepine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Midazolam EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Midazolam EP Impurity A
Catalogue No.	VQ-044844
CAS Number	59469-02-2
IUPAC name	8-chloro-6-(2-fluorophenyl)-1-methyl-5-nitroso-4,6-dihydroimidazo[1,5-a][1,4]benzodiazepine
Molecular formula	C₁₈H₁₄ClFN₄O
Molecular weight	356.8 g/mol
Exact mass	356.084
Grade	Reference Standard
HSN code	38229090
InChIKey	WWHCXZOITOASCT-UHFFFAOYSA-N
SMILES	CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(N(C2)N=O)C4=CC=CC=C4F
PubChem CID	12802064

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	0 / 5
TPSA	50.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Midazolam EP Impurity A?

The CAS Registry Number of N-Nitroso Midazolam EP Impurity A is 59469-02-2.

What is the molecular formula and molecular weight of N-Nitroso Midazolam EP Impurity A?

N-Nitroso Midazolam EP Impurity A has the molecular formula C18H14ClFN4O and a molecular weight of 356.8 g/mol. Its IUPAC name is 8-chloro-6-(2-fluorophenyl)-1-methyl-5-nitroso-4,6-dihydroimidazo[1,5-a][1,4]benzodiazepine.

What is N-Nitroso Midazolam EP Impurity A used for?

N-Nitroso Midazolam EP Impurity A is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Midazolam EP Impurity A can I order?

We supply N-Nitroso Midazolam EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Midazolam EP Impurity A?

Yes. Every lot of N-Nitroso Midazolam EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Midazolam EP Impurity A be shipped internationally?

Yes. We export N-Nitroso Midazolam EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.