N-Acetyl-L-Cysteine-d3

Name: N-Acetyl-L-Cysteine-d3
Brand: Vaqora Chemicals
SKU: VQ-029014

About N-Acetyl-L-Cysteine-d3

N-Acetyl-L-Cysteine-d3 (CAS 131685-11-5) is a stable isotope labelled analogue related to Acetylcysteine offered by Vaqora Chemicals. The compound has the formula C5H9NO3S, corresponding to a molecular weight of 166.22 g/mol. Its systematic (IUPAC) name is (2R)-3-sulfanyl-2-[(2,2,2-trideuterioacetyl)amino]propanoic acid. Alternative names: Acetylcysteine-D3 and N-Acetyl-d3-L-cysteine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Acetylcysteine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Acetyl-L-Cysteine-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Acetylcysteine

View every impurity, metabolite and intermediate we list for Acetylcysteine.

Acetylcysteine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl-L-Cysteine-d3
Catalogue No.	VQ-029014
CAS Number	131685-11-5
IUPAC name	(2R)-3-sulfanyl-2-[(2,2,2-trideuterioacetyl)amino]propanoic acid
Molecular formula	C₅H₉NO₃S
Molecular weight	166.22 g/mol
Exact mass	166.0491
Grade	Reference Standard
HSN code	38229090
InChIKey	PWKSKIMOESPYIA-OSIBIXDNSA-N
SMILES	[2H]C([2H])([2H])C(=O)N[C@@H](CS)C(=O)O
PubChem CID	54211755

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	3 / 4
TPSA	67.4 Å²
Synonyms	Acetylcysteine-D3, (2R)-3-sulfanyl-2-((2,2,2-trideuterioacetyl)amino)propanoic acid, N-Acetyl-d3-L-cysteine, L-Cysteine, N-(acetyl-d3)- (9CI), N-Acetylcysteine-d3, (acetyl-d3)-L-cysteine, N-trideuteroacetyl-l-cysteine, TMID-1053

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl-L-Cysteine-d3?

The CAS Registry Number of N-Acetyl-L-Cysteine-d3 is 131685-11-5. It is also known as Acetylcysteine-D3, (2R)-3-sulfanyl-2-((2,2,2-trideuterioacetyl)amino)propanoic acid, N-Acetyl-d3-L-cysteine.

What is the molecular formula and molecular weight of N-Acetyl-L-Cysteine-d3?

N-Acetyl-L-Cysteine-d3 has the molecular formula C5H9NO3S and a molecular weight of 166.22 g/mol. Its IUPAC name is (2R)-3-sulfanyl-2-[(2,2,2-trideuterioacetyl)amino]propanoic acid.

What is N-Acetyl-L-Cysteine-d3 used for?

N-Acetyl-L-Cysteine-d3 is supplied as a characterised reference material related to Acetylcysteine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl-L-Cysteine-d3 can I order?

We supply N-Acetyl-L-Cysteine-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl-L-Cysteine-d3?

Yes. Every lot of N-Acetyl-L-Cysteine-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl-L-Cysteine-d3 be shipped internationally?

Yes. N-Acetyl-L-Cysteine-d3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.