N-Desmethyl Imatinib-d8

Name: N-Desmethyl Imatinib-d8
Brand: Vaqora Chemicals
SKU: VQ-037667

About N-Desmethyl Imatinib-d8

Vaqora Chemicals supplies N-Desmethyl Imatinib-d8, a stable isotope labelled analogue related to Imatinib registered under CAS number 1185103-28-9. With the molecular formula C28H29N7O, it has a molar mass of 487.6 g/mol. Alternative names: N-Desmethyl gleevec-d8.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Imatinib and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Imatinib-d8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Imatinib-d8
Catalogue No.	VQ-037667
CAS Number	1185103-28-9
IUPAC name	N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)methyl]benzamide
Molecular formula	C₂₈H₂₉N₇O
Molecular weight	487.6 g/mol
Exact mass	487.2936
Grade	Reference Standard
HSN code	38229090
InChIKey	BQQYXPHRXIZMDM-DBVREXLBSA-N
SMILES	[2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])CC2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5)([2H])[2H])[2H]
PubChem CID	44816894

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 7
TPSA	95.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Imatinib-d8?

The CAS Registry Number of N-Desmethyl Imatinib-d8 is 1185103-28-9. It is also known as N-Desmethyl gleevec-d8.

What is the molecular formula and molecular weight of N-Desmethyl Imatinib-d8?

N-Desmethyl Imatinib-d8 has the molecular formula C28H29N7O and a molecular weight of 487.6 g/mol. Its IUPAC name is N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)methyl]benzamide.

What is N-Desmethyl Imatinib-d8 used for?

N-Desmethyl Imatinib-d8 is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Imatinib-d8 can I order?

We supply N-Desmethyl Imatinib-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Imatinib-d8?

Yes. Every lot of N-Desmethyl Imatinib-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Imatinib-d8 be shipped internationally?

Yes. We export N-Desmethyl Imatinib-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.