N-Desmethyl -N-Nitroso Imatinib

Name: N-Desmethyl -N-Nitroso Imatinib
Brand: Vaqora Chemicals
SKU: VQ-031171

About N-Desmethyl -N-Nitroso Imatinib

Vaqora Chemicals supplies N-Desmethyl -N-Nitroso Imatinib, a nitrosamine impurity of Imatinib registered under CAS number 2816369-80-7. Formula C28H28N8O2, molecular weight 508.6 g/mol. Systematically, it is named N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(4-nitrosopiperazin-1-yl)methyl]benzamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Imatinib, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Imatinib

View every impurity, metabolite and intermediate we list for Imatinib.

Imatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl -N-Nitroso Imatinib
Catalogue No.	VQ-031171
CAS Number	2816369-80-7
IUPAC name	N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(4-nitrosopiperazin-1-yl)methyl]benzamide
Molecular formula	C₂₈H₂₈N₈O₂
Molecular weight	508.6 g/mol
Exact mass	508.2335
Grade	Reference Standard
HSN code	38229090
InChIKey	VLMTWVXKQVBYLS-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)N=O)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	169444186

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 9
TPSA	116 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl -N-Nitroso Imatinib?

The CAS Registry Number of N-Desmethyl -N-Nitroso Imatinib is 2816369-80-7.

What is the molecular formula and molecular weight of N-Desmethyl -N-Nitroso Imatinib?

N-Desmethyl -N-Nitroso Imatinib has the molecular formula C28H28N8O2 and a molecular weight of 508.6 g/mol. Its IUPAC name is N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(4-nitrosopiperazin-1-yl)methyl]benzamide.

What is N-Desmethyl -N-Nitroso Imatinib used for?

N-Desmethyl -N-Nitroso Imatinib is supplied as a characterised reference material related to Imatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl -N-Nitroso Imatinib can I order?

We supply N-Desmethyl -N-Nitroso Imatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl -N-Nitroso Imatinib?

Yes. Every lot of N-Desmethyl -N-Nitroso Imatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl -N-Nitroso Imatinib be shipped internationally?

Yes. We export N-Desmethyl -N-Nitroso Imatinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.