N-Desmethyl Sildenafil-d8

Name: N-Desmethyl Sildenafil-d8
Brand: Vaqora Chemicals
SKU: VQ-033841

About N-Desmethyl Sildenafil-d8

N-Desmethyl Sildenafil-d8 (CAS 1185168-06-2) is a stable isotope labelled analogue related to Sildenafil offered by Vaqora Chemicals. The compound has the formula C21H28N6O4S, corresponding to a molecular weight of 468.6 g/mol. Alternative names: TMID-0050.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Desmethyl Sildenafil-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Sildenafil-d8
Catalogue No.	VQ-033841
CAS Number	1185168-06-2
IUPAC name	5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one
Molecular formula	C₂₁H₂₈N₆O₄S
Molecular weight	468.6 g/mol
Exact mass	468.2395
Grade	Reference Standard
HSN code	38229090
InChIKey	UZTKBZXHEOVDRL-PMCMNDOISA-N
SMILES	[2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])S(=O)(=O)C2=CC(=C(C=C2)OCC)C3=NC4=C(C(=O)N3)N(N=C4CCC)C)([2H])[2H])[2H]
PubChem CID	136219910

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	2 / 8
TPSA	126 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Sildenafil-d8?

The CAS Registry Number of N-Desmethyl Sildenafil-d8 is 1185168-06-2. It is also known as TMID-0050.

What is the molecular formula and molecular weight of N-Desmethyl Sildenafil-d8?

N-Desmethyl Sildenafil-d8 has the molecular formula C21H28N6O4S and a molecular weight of 468.6 g/mol. Its IUPAC name is 5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one.

What is N-Desmethyl Sildenafil-d8 used for?

N-Desmethyl Sildenafil-d8 is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Sildenafil-d8 can I order?

We supply N-Desmethyl Sildenafil-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Sildenafil-d8?

Yes. Every lot of N-Desmethyl Sildenafil-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Sildenafil-d8 be shipped internationally?

Yes. We export N-Desmethyl Sildenafil-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.