N-Desmethyl Topotecan
Synonyms: Topotecan N-Desmethyl Metabolite
N-Desmethyl Topotecan (CAS 190710-79-3) – Topotecan impurity standard. C22H21N3O5, MW 407.4. Supplied by Vaqora Chemicals with COA, exported worldwide.
About N-Desmethyl Topotecan
N-Desmethyl Topotecan is a metabolite or degradation product of Topotecan carrying the CAS registry number 190710-79-3. Formula C22H21N3O5, molecular weight 407.4 g/mol. Alternative names: Topotecan N-Desmethyl Metabolite.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
Analytical teams use this compound to identify metabolites and degradants of Topotecan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Topotecan is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Topotecan.
Topotecan impuritiesSpecifications & identifiers
| Product name | N-Desmethyl Topotecan |
|---|---|
| Catalogue No. | VQ-034364 |
| CAS Number | 190710-79-3 |
| IUPAC name | (19S)-19-ethyl-7,19-dihydroxy-8-(methylaminomethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione |
| Molecular formula | C22H21N3O5 |
| Molecular weight | 407.4 g/mol |
| Exact mass | 407.1481 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | ZWUJOGCYOWLZFL-QFIPXVFZSA-N |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CNC)O)N=C4C3=C2)O |
| PubChem CID | 9931216 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.6 |
| H-bond donors / acceptors | 3 / 7 |
| TPSA | 112 Ų |
Documents
Frequently asked questions
What is the CAS number of N-Desmethyl Topotecan?
The CAS Registry Number of N-Desmethyl Topotecan is 190710-79-3. It is also known as Topotecan N-Desmethyl Metabolite.
What is the molecular formula and molecular weight of N-Desmethyl Topotecan?
N-Desmethyl Topotecan has the molecular formula C22H21N3O5 and a molecular weight of 407.4 g/mol.
What is N-Desmethyl Topotecan used for?
N-Desmethyl Topotecan is supplied as a characterised reference material related to Topotecan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-Desmethyl Topotecan can I order?
We supply N-Desmethyl Topotecan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-Desmethyl Topotecan?
Yes. Every lot of N-Desmethyl Topotecan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-Desmethyl Topotecan be shipped internationally?
Yes. We export N-Desmethyl Topotecan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about N-Desmethyl Topotecan
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