5-Hydroxy Topotecan-d6

Name: 5-Hydroxy Topotecan-d6
Brand: Vaqora Chemicals
SKU: VQ-028466

About 5-Hydroxy Topotecan-d6

5-Hydroxy Topotecan-d6 (CAS 504413-73-4) is a stable isotope labelled analogue related to Topotecan offered by Vaqora Chemicals. Formula C23H23N3O6, molecular weight 437.4 g/mol. It is also known as 5-Hydroxy Topotecan Dihydrochloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Hydroxy Topotecan-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Topotecan

View every impurity, metabolite and intermediate we list for Topotecan.

Topotecan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxy Topotecan-d6
Catalogue No.	VQ-028466
CAS Number	504413-73-4
IUPAC name	(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,12,19-trihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Molecular formula	C₂₃H₂₃N₃O₆
Molecular weight	437.4 g/mol
Exact mass	437.1587
Grade	Reference Standard
HSN code	38229090
InChIKey	IKBVYIZOTSVDNQ-AKRCKQFNSA-N
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3C(C4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O)O
PubChem CID	10113956

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	3 / 8
TPSA	123 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxy Topotecan-d6?

The CAS Registry Number of 5-Hydroxy Topotecan-d6 is 504413-73-4. It is also known as 5-Hydroxy Topotecan Dihydrochloride, 5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers).

What is the molecular formula and molecular weight of 5-Hydroxy Topotecan-d6?

5-Hydroxy Topotecan-d6 has the molecular formula C23H23N3O6 and a molecular weight of 437.4 g/mol.

What is 5-Hydroxy Topotecan-d6 used for?

5-Hydroxy Topotecan-d6 is supplied as a characterised reference material related to Topotecan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxy Topotecan-d6 can I order?

We supply 5-Hydroxy Topotecan-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxy Topotecan-d6?

Yes. Every lot of 5-Hydroxy Topotecan-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxy Topotecan-d6 be shipped internationally?

Yes. We export 5-Hydroxy Topotecan-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.