N-Methylated diphenhydramine

Name: N-Methylated diphenhydramine
Brand: Vaqora Chemicals
SKU: VQ-048035

About N-Methylated diphenhydramine

Vaqora Chemicals supplies N-Methylated diphenhydramine, an impurity of Diphenhydramine registered under CAS number 29869-74-7. Its molecular formula is C18H24NO+ and its molecular weight is 270.4 g/mol. Systematically, it is named 2-benzhydryloxyethyl(trimethyl)azanium. It is also known as Diphenhydramine N-methylated or Mefenidramium.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Diphenhydramine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Diphenhydramine

View every impurity, metabolite and intermediate we list for Diphenhydramine.

Diphenhydramine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methylated diphenhydramine
Catalogue No.	VQ-048035
CAS Number	29869-74-7
IUPAC name	2-benzhydryloxyethyl(trimethyl)azanium
Molecular formula	C₁₈H₂₄NO⁺
Molecular weight	270.4 g/mol
Exact mass	270.1858
Grade	Reference Standard
HSN code	38229090
InChIKey	LTWUEHSXIKQTIK-UHFFFAOYSA-N
SMILES	C[N+](C)(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2
PubChem CID	26536

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 1
TPSA	9.2 Å²
Synonyms	Diphenhydramine N-methylated, Mefenidramium, Mefenidramium cation, (2-(Diphenylmethoxy)ethyl)trimethylammonium, Ethanaminium, 2-(diphenylmethoxy)-N,N,N-trimethyl-, 2-(Diphenylmethoxy)-N,N,N-trimethylethan-1-aminium

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methylated diphenhydramine?

The CAS Registry Number of N-Methylated diphenhydramine is 29869-74-7. It is also known as Diphenhydramine N-methylated, Mefenidramium, Mefenidramium cation.

What is the molecular formula and molecular weight of N-Methylated diphenhydramine?

N-Methylated diphenhydramine has the molecular formula C18H24NO+ and a molecular weight of 270.4 g/mol. Its IUPAC name is 2-benzhydryloxyethyl(trimethyl)azanium.

What is N-Methylated diphenhydramine used for?

N-Methylated diphenhydramine is supplied as a characterised reference material related to Diphenhydramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methylated diphenhydramine can I order?

We supply N-Methylated diphenhydramine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methylated diphenhydramine?

Yes. Every lot of N-Methylated diphenhydramine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methylated diphenhydramine be shipped internationally?

Yes. We export N-Methylated diphenhydramine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.