N-Methylsaccharin

Name: N-Methylsaccharin
Brand: Vaqora Chemicals
SKU: VQ-013645

About N-Methylsaccharin

N-Methylsaccharin (CAS 15448-99-4) is a process intermediate or related compound of Piroxicam offered by Vaqora Chemicals. Its molecular formula is C8H7NO3S and its molecular weight is 197.21 g/mol. Its systematic (IUPAC) name is 2-methyl-1,1-dioxo-1,2-benzothiazol-3-one. It is also known as N-Methylbenzoic sulfimide or Methylsaccharin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Piroxicam, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Methylsaccharin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Piroxicam

View every impurity, metabolite and intermediate we list for Piroxicam.

Piroxicam impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methylsaccharin
Catalogue No.	VQ-013645
CAS Number	15448-99-4
IUPAC name	2-methyl-1,1-dioxo-1,2-benzothiazol-3-one
Molecular formula	C₈H₇NO₃S
Molecular weight	197.21 g/mol
Exact mass	197.0147
Grade	Reference Standard
HSN code	2933
InChIKey	DDIIAJRLFATEEE-UHFFFAOYSA-N
SMILES	CN1C(=O)C2=CC=CC=C2S1(=O)=O
PubChem CID	27290

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 3
TPSA	62.8 Å²
Synonyms	2-Methyl-1,2-benzisothiazolin-3-one 1,1-dioxide, 2-Methylbenzo[d]isothiazol-3(2H)-one1,1-dioxide, N-Methylbenzoic sulfimide, 2-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide, 2-Methylbenzo[d]isothiazol-3(2H)-one 1,1-dioxide, 2-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide, 1,2-Benzisothiazolin-3-one, 2-methyl-, 1,1-dioxide, 2-Methyl-1,2-benzisothiazole-3(2H)-one-1,1-dioxide, 1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide, Methylsaccharin, methyl saccharine, 2-Methyl-1,1-dioxide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methylsaccharin?

The CAS Registry Number of N-Methylsaccharin is 15448-99-4. It is also known as 2-Methyl-1,2-benzisothiazolin-3-one 1,1-dioxide, 2-Methylbenzo[d]isothiazol-3(2H)-one1,1-dioxide, N-Methylbenzoic sulfimide.

What is the molecular formula and molecular weight of N-Methylsaccharin?

N-Methylsaccharin has the molecular formula C8H7NO3S and a molecular weight of 197.21 g/mol. Its IUPAC name is 2-methyl-1,1-dioxo-1,2-benzothiazol-3-one.

What is N-Methylsaccharin used for?

N-Methylsaccharin is supplied as a characterised reference material related to Piroxicam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methylsaccharin can I order?

We supply N-Methylsaccharin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methylsaccharin?

Yes. Every lot of N-Methylsaccharin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methylsaccharin be shipped internationally?

Yes. N-Methylsaccharin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.