Piroxicam EP Impurity B

Name: Piroxicam EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023506

About Piroxicam EP Impurity B

Piroxicam EP Impurity B is a pharmacopeial impurity of Piroxicam carrying the CAS registry number 65897-46-3. Its molecular formula is C14H11N3O4S and its molecular weight is 317.32 g/mol. Systematically, it is named 4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2H-1lambda6,2-benzothiazine-3-carboxamide. It is also known as Piroxicam - Impurity B or Desmethyl piroxicam.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Piroxicam, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Piroxicam EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Piroxicam

View every impurity, metabolite and intermediate we list for Piroxicam.

Piroxicam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Piroxicam EP Impurity B
Catalogue No.	VQ-023506
CAS Number	65897-46-3
IUPAC name	4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2H-1lambda6,2-benzothiazine-3-carboxamide
Molecular formula	C₁₄H₁₁N₃O₄S
Molecular weight	317.32 g/mol
Exact mass	317.047
Grade	Reference Standard
HSN code	38229090
InChIKey	XRXYFCIBSPQECM-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=CC=N3)O
PubChem CID	54719424

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	3 / 6
TPSA	117 Å²
Synonyms	Piroxicam - Impurity B, Desmethyl piroxicam, 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-2-pyridinyl-, 1,1-dioxide, 4-Hydroxy-N-(pyridin-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, Piroxicam specified impurity B, Desmethyl Piroxicam (Piroxicam Impurity B), 4-hydroxy-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6,2-benzothiazine-3-carboxamide, Piroxicam Impurity B, 4-Hydroxy-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide, 4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide, 4-hydroxy-1,1-dioxo-N-(2-pyridyl)-2H-1lambda6,2-benzothiazine-3-carboxamide, 4-Hydroxy-1,1-dioxo-N-(pyridin-2-yl)-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxamide

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Piroxicam EP Impurity B?

The CAS Registry Number of Piroxicam EP Impurity B is 65897-46-3. It is also known as Piroxicam - Impurity B, Desmethyl piroxicam, 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-2-pyridinyl-, 1,1-dioxide.

What is the molecular formula and molecular weight of Piroxicam EP Impurity B?

Piroxicam EP Impurity B has the molecular formula C14H11N3O4S and a molecular weight of 317.32 g/mol. Its IUPAC name is 4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2H-1lambda6,2-benzothiazine-3-carboxamide.

What is Piroxicam EP Impurity B used for?

Piroxicam EP Impurity B is supplied as a characterised reference material related to Piroxicam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Piroxicam EP Impurity B can I order?

We supply Piroxicam EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Piroxicam EP Impurity B?

Yes. Every lot of Piroxicam EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Piroxicam EP Impurity B be shipped internationally?

Yes. Piroxicam EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.