N-Nitroso-N-methylurea

Name: N-Nitroso-N-methylurea
Brand: Vaqora Chemicals
SKU: VQ-032551

About N-Nitroso-N-methylurea

N-Nitroso-N-methylurea is a nitrosamine impurity of Urea carrying the CAS registry number 684-93-5. With the molecular formula C2H5N3O2, it has a molar mass of 103.08 g/mol. The IUPAC name is 1-methyl-1-nitrosourea. Alternative names: N-Methyl-N-nitroso Urea and N-Methyl-N-nitrosourea.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso-N-methylurea in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Urea

View every impurity, metabolite and intermediate we list for Urea.

Urea impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-N-methylurea
Catalogue No.	VQ-032551
CAS Number	684-93-5
IUPAC name	1-methyl-1-nitrosourea
Molecular formula	C₂H₅N₃O₂
Molecular weight	103.08 g/mol
Exact mass	103.0382
Grade	Reference Standard
HSN code	38229090
InChIKey	ZRKWMRDKSOPRRS-UHFFFAOYSA-N
SMILES	CN(C(=O)N)N=O
PubChem CID	12699

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	75.8 Å²
Synonyms	N-Methyl-N-nitroso Urea, N-Methyl-N-nitrosourea, Urea, N-methyl-N-nitroso-, 1-Nitroso-1-methylurea, N-Nitroso-N-methylcarbamide, Urea, 1-methyl-1-nitroso-, Methylnitroso-harnstoff, SRI 859, N-Methyl-N-nitroso-harnstoff, N-Nitroso-N-methyl-harnstoff, Carbamide, N-methyl-N-nitroso-

Safety & hazard information (GHS)

Flammable

Toxic

Health hazard

Signal word: Danger

Hazard statements

H228Flammable solid
H301Toxic if swallowed
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P210, P240, P241, P264, P270, P280, P301 + P316, P318, P321, P330, P370 + P378, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-N-methylurea?

The CAS Registry Number of N-Nitroso-N-methylurea is 684-93-5. It is also known as N-Methyl-N-nitroso Urea, N-Methyl-N-nitrosourea, Urea, N-methyl-N-nitroso-.

What is the molecular formula and molecular weight of N-Nitroso-N-methylurea?

N-Nitroso-N-methylurea has the molecular formula C2H5N3O2 and a molecular weight of 103.08 g/mol. Its IUPAC name is 1-methyl-1-nitrosourea.

What is N-Nitroso-N-methylurea used for?

N-Nitroso-N-methylurea is supplied as a characterised reference material related to Urea. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-N-methylurea can I order?

We supply N-Nitroso-N-methylurea in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-N-methylurea?

Yes. Every lot of N-Nitroso-N-methylurea is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-N-methylurea be shipped internationally?

Yes. N-Nitroso-N-methylurea is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.